型號:9603-400-B、4003-400-B
聯(lián)系人:程園
聯(lián)系電話:18611717737
品牌:mimetas
讓復(fù)雜的組織研究變得j為簡單
于為復(fù)雜的3D生物學(xué)創(chuàng)造簡單的設(shè)備和裝置。通過對較容易控制的灌注血管，共培養(yǎng)和化微環(huán)境的使用，以至于你不會察覺到自己使用的裝置可能是的組織培養(yǎng)平臺。通過OrganoPlate®這些愿景都能實現(xiàn)。OrganoPlate® 是3D組織模式的未來。
顯而易見社會需要更好的藥品。而為了達(dá)到這一點，需要在充分考慮人類和生理上相關(guān)性的基礎(chǔ)上，研發(fā)更好的疾病模型。作為真正的信息工具，需要在兼容化合物的同時和還具有高通量讀出功能。作為organ-on-a-chip生物學(xué)真正的先驅(qū)者，本公司可開展任何通量的人體組織和疾病模型相關(guān)的OrganoPlate®產(chǎn)業(yè)。
OrganoPlate®是一種基于微流體技術(shù)3D細(xì)胞培養(yǎng)板，可在一塊板上實現(xiàn)96個單組織模型的培養(yǎng)。Phaseguides?能夠以3D方式j(luò)確地重新定義細(xì)胞及其培養(yǎng)基，實現(xiàn)細(xì)胞間的相互作用以及前所未有品質(zhì)的成像和定量操作。
The OrganoPlate 2-lane 400 features 96 independent culture cells, each supporting one in-gel culture and a perfusion channel, that can contain a perfused tubular tissue. The lanes are 400 micron-wide. Four wells of the 384-well-plate user interface connect to each microfluidic network.
The 2-lane OrganoPlate® is a microfluidic 3D culture plate, supporting up to 96 tissue models on a single plate. The OrganoPlate contains Phaseguides?, a proprietary, passive liquid handling technology for membrane-free definition of tissues in microfluidic chambers. The OrganoPlate is based on the industry-standard 384?well plate for full compatibility with liquid handling- and readout equipment.
The OrganoPlate 2-lane 400 supports a range of cell types, including neurons, endothelial tubules, hepatocytes, CaCo2 cells, organoids and kidney epithelial proximal tubules. This plate allows for culture in-gel, tubular culture against the gel and combinations of in-gel and tubular culture.
For more information on tissue model design in the OrganoPlate 2-lane 400, read this.
A culture cell is a fully autonomous organ-on-a-chip culture unit in the OrganoPlate®. The OrganoPlate 3-lane contains 40 3-lane culture cells, the 2-lane 96 2-lane culture cells, all in a standard 384 well plate format. The culture cells on a single OrganoPlate may be used all at once in an experiment, but can also be used individually.
A lane is an individually addressable part of a culture cell in the OrganoPlate®. The OrganoPlate 3-lane features 3 adjacent lanes per culture cell, 2 of which are perfusable. The OrganoPlate 2-lane features 2 adjacent lanes per culture cells, of which 1 is perfusable. A single lane may contain cells in an ECM gel, a perfused epithelial tubule or just medium flow. By virtue of patented Phaseguide technology, no physical barriers are present between the lanes in the OrganoPlate, allowing co-cultured cells in adjacent lanes to interact and migrate freely.
The materials and equipment you need to work with the OrganoPlate® 2-lane 400 are listed below.
We will provide you with detailed instructions for use, including materials and equipment.
The OrganoPlate 3-lane features 40 independent culture cells, each supporting adjacent in-gel culture and 2 perfusion channels, that can contain perfused tubular tissues. The 3-lane models supports apical and basal access to epithelial and endothelial tubules, allowing barrier integrity and transport assays.
The lanes are 400 micron wide. Six wells of the 384-well-plate user interface connect to each microfluidic network in a 9x9 well grid, the central well provides viewing access to the microtissue.
The OrganoPlate® 3-lane is a microfluidic 3D culture plate, supporting up to 40 tissue models on a single plate. The OrganoPlate contains Phaseguides?, a proprietary, passive liquid handling technology for membrane-free definition of tissues in microfluidic chambers. The OrganoPlate is based on the industry-standard 384?well plate for full compatibility with liquid handling- and readout equipment.
The OrganoPlate 3-lane 400 supports a range of cell types, including neurons, endothelial tubules, hepatocytes, CaCo2 cells, organoids and kidney epithelial proximal tubules. This plate allows for culture in-gel, tubular culture against the gel and combinations of in-gel and tubular culture in 3 lanes, allowing cells to interact through the absence of separating membranes or barriers.
Read this for more information on tissue model design in the OrganoPlate 3-lane 400.
A culture cell is a fully autonomous organ-on-a-chip culture unit in the OrganoPlate®. The OrganoPlate 3-lane contains 40 3-lane culture cells, a 2-lane 96 2-lane culture cells, all in a standard 384 well plate format. The culture cells on a single OrganoPlate may be used all at once in an experiment, but can also be used individually.
A lane is an individually addressable part of a culture cell in the OrganoPlate®. A 3-lane OrganoPlate features 3 adjacent lanes per culture cell, of which 2 are perfusable. The OrganoPlate 2-lane features 2 adjacent lanes per culture cells, of which 1 is perfusable. A single lane may contain cells in an ECM gel, a perfused epithelial tubule or just medium flow. By virtue of patented Phaseguide technology, no physical barriers are present between the lanes in the OrganoPlate, allowing co-cultured cells in adjacent lanes to interact and migrate freely.
The materials and equipment you need to work with the OrganoPlate® 2-lane 400 are listed below.
We will provide you with detailed instructions for use, including materials and equipment.
The Perfusion Rocker? Mini provides a continuous medium flow in the OrganoPlate® with minimal settings required. Perfusion Rockers? feature optimized angles, time settings and programs for use with the OrganoPlate®, in contrast to ordinary continuous see-saw rockers.
Medium perfusion (flow) in the OrganoPlate® is established by passive leveling of liquids. The perfusion can be maintained indefinitely by placing the OrganoPlate® on a MIMETAS Perfusion Rocker?. This customized rocker platform fits easily in an incubator and enables interval rocking (switching sides every 5-15 minutes), as well as adjustable rocking angles.
Minimal settings are required for pump- and tube-free perfusion in OrganoPlates®. Perfusion Rockers? feature optimized time- and angle settings and programs for use with OrganoPlates®. The Perfusion Rocker comes in two versions: Perfusion Rocker? Mini for 2 stacks of plates and the Perfusion Rocker?Maxi for 4 stacks of plates. Both versions are suitable for use in standard tissue culture incubators, the Perfusion Rocker? Maxi is available on request.
OrganoPlate® 2-lane
Product no. 9603-400-B
Left: Features and applications of the 2-lane and 3-lane OrganoPlate Right: Microfluidic design of a single culture cell
Supported tissue models
What is a culture cell in the OrganoPlate®?
What is a lane in an OrganoPlate® culture cell?
Materials and equipment
OrganoPlate® 3-lane
Product no. 4003-400-B
Left: Features and applications of the 2-lane and 3-lane OrganoPlate Right: Microfluidic design of a single culture cell
Supported tissue models
What is a culture cell in the OrganoPlate®?
What is a lane in an OrganoPlate® culture cell?
Materials and equipment
Perfusion Rocker Mini
Operation
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