細胞牽張力共培養(yǎng)系統(tǒng)，flexercell transwell holder，細胞牽張共培養(yǎng)系統(tǒng)，細胞牽拉共培養(yǎng)系統(tǒng)
型號:FX-5000T
聯(lián)系人:李先生
聯(lián)系電話:18618101725
品牌:flexercell
FX-5000T細胞牽張拉伸應(yīng)力加載系統(tǒng)(flexercell FX5000 Tension system)
亮點：
1）該系統(tǒng)對二維、三維細胞和組織各種培養(yǎng)物提供軸向和圓周應(yīng)力加載；不但具有雙軸向拉伸力加載，還具備單軸向加力功能
2）計算機控制的應(yīng)力加載系統(tǒng)，為體外培育的細胞提供j確的、可控制的、可重復(fù)的、靜態(tài)的或者周期性的應(yīng)力變化。
3）使用真空泵，抻拉培養(yǎng)板底部的彈性硅膠模，細胞培養(yǎng)板底部高伸展度可達到33%，通過氣體裝置可以自動調(diào)節(jié)和控制應(yīng)力。
4）基于柔性膜基底變形、受力均勻;
5）可實時觀察細胞、組織在應(yīng)力作用下的反應(yīng);
6）具的flexstop隔離閥可使同一塊培養(yǎng)板力的一部分培養(yǎng)孔的細胞受力，一部分培養(yǎng)孔的細胞不受力，方便對比實驗;
7）與壓力傳導(dǎo)儀整合，同時兼?zhèn)涠嗤ǖ兰毎麎毫虞d功能;
8）與Flex Flow平行板流室配套，可在牽拉細胞的同時施加流體切應(yīng)力;
9）多達4通道，可4個不同程序同時運行，進行多個不同拉伸形變率對比實驗；
10）同一程序中可以運行多種頻率，多種振幅和多種波形；
11）加載模擬波形種類豐富：靜態(tài)波形、正旋波形、心動波形、三角波形、矩形以及各種te制波形；
12）更好地控制在超低或超高應(yīng)力下的波形；
13)電腦系統(tǒng)對牽張拉伸力加載周期、大小、頻率、持續(xù)時間j確智能調(diào)控
14)加載分析各種細胞在牽張拉應(yīng)力刺激下的生物化學(xué)反應(yīng)
15)伸展度范圍廣：0-33%
16)牽拉頻率范圍廣：0.01-5Hz
17)可以在6孔板和24孔牽張拉伸培養(yǎng)板實現(xiàn)不同細胞系的共培養(yǎng)
flexercell® Transwell Holder 圖
圖 1
Holders sit atop a 6-well or a 24-well flexercell® Culture Plate (圖 1) and allow users to run co-culture or cell migration assays with standard transwells.
- Analyze cell migration in response to strain.
- Run experiments with unstrained control cells and the strained cells in the same culture plate well.
- Compatible with Transwells for 6-well* and 24-well** plates.
*6-well inserts with a 24 mm insert diameter or with a 37-41 mm outer lip diameter and 15.5-16.5 mm height.
**24-well inserts with a 6.5 mm insert diameter or with a 16.9-18.8 mm outer lip diameter and 15.5-16.5 mm height.
Applications of Transwell® with flexercell® Culture Plates
- Co-Culture - Culture two different cell types in the presence or absence of mechanical load. Isolate direct and auto/paracrine effects of mechanical load.
- Cell Migration - Examine the paracrine/autocrine effects of substrate strain on cell migration.
- Transport & Permeability - Examine drug transport in response to the paracrine effects of mechanical load.
- Cell Polarity - Analyze the formation of polarized layers of cells in response to the paracrine effects brought about by mechanical load. In addition, examine epithelial penetration by pathogens, wound repair, ion channel activity, and other processes that rely on well-differentiated polarized cell layers.
- Chemotaxis & Invasion - Analyze the effects of mechanical load on inflammatory cell migration, metastatic invasion, and angiogenesis.
 Figure 1: Schematic of a Transwell Holder with a Transwell supported atop the rubber membrane in the well of BioFlex® culture plate. |
