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產(chǎn)品名稱

BMS 605541

產(chǎn)品貨號

Axon 2837 CAS [639858-32-5] MF C19H17F2N5OSMW 401.43 Purity: 98% Soluble in DMSO Recently added

產(chǎn)品價(jià)格

現(xiàn)貨詢價(jià)，電話：010-67529703

產(chǎn)品規(guī)格

產(chǎn)品品牌

axonmedchem

產(chǎn)品概述

產(chǎn)品詳情

BMS 605541

Based on 2 reference(s) in Google Scholar 8 10 2

Axon 2837

CAS [639858-32-5]

MF C19H17F2N5OS
MW 401.43

Purity: 98%
Soluble in DMSO

Recently added

BMS 605541

Description

BMS 605541 is potent, selective, orally active, ATP-competitive inhibitor of VEGFR2 (IC50 value of 23 nm). Orally active in human lung (L2987) and colon (HCT-116) carcinoma xenograft models at multiple dose levels.

RM Borzilleri et al. Discovery and evaluation?of N-cyclopropyl- 2,4-difluoro-5-((2-(pyridin-2-ylamino)thiazol-5- ylmethyl)amino)benzamide?(BMS-605541), a selective and orally efficacious inhibitor of vascular endothelial growth factor receptor-2. J Med Chem. 2006 Jun 29;49(13):3766-9.

Certificate of Analysis
Material Safety Data Sheet

Angiogenesis Cell Signaling & Oncology VEGFR RTK class IV; EC 2.7.10.1

Potent, selective, orally active, and ATP-competitive VEGFR2 inhibitor

Chemical name

N-Cyclopropyl-2,4-difluoro-5-((2-(pyridin-2-ylamino)thiazol-5-yl)methylamino)benzamide

Parent CAS No.

[639858-32-5]

產(chǎn)品資料

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