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產(chǎn)品名稱

Sonepiprazole hydrochloride - PNU 101387

產(chǎn)品貨號(hào)

Axon 2115 CAS [170857-36-0] MF C21H27N3O3S.HClMW 437.98 Purity: 98% Optical purity: Optically pure Soluble in DMSO Description Selective dopamine D4 antagonist; Displayed high affinity (Ki = 10 nM) and selectivity for the D4 receptor expressed in clonal cell lines, lacking measurable affinity for other dopamine receptors, and noradrenalin, serotonin and histamine receptor families (Ki > 2000 nM) References Certificates Categories Extra info PA Broderick et al. Clozapine, haloperidol, and the D4 antagonist PNU-101387G: in vivo effects on mesocortical, mesolimbic, and nigrostriatal dopamine and serotonin release. J. Neural. Transm. 1998, 105(6-7), 749-767.? ? KM Merchant et al. Pharmacological characterization of U-101387, a dopamine D4 receptor selective antagonist. J. Pharmacol. Exp. Ther. 1996, 279(3), 1392-1403.? Certificate of Analysis Material Safety Data Sheet CNS D4 A17 Pfizer Licensed Products Selective dopamine D4 antagonist Chemical name (S)-4-(4-(2-(isochroman-1-yl)ethyl)piperazin-1-yl)benzenesulfonamide hydrochloride Source information Pfizer compound; Sold for research purposes under agreement from Pfizer Inc. Parent CAS No. [170858-33-0] Order Size Unit Price Stock 5 mg €85.00 In Stock

產(chǎn)品價(jià)格

現(xiàn)貨詢價(jià)，電話：010-67529703

產(chǎn)品規(guī)格

產(chǎn)品品牌

axonmedchem

產(chǎn)品概述

產(chǎn)品詳情

Sonepiprazole hydrochloride - PNU 101387

Based on 16 reference(s) in Google Scholar 9 10 16

Axon 2115

CAS [170857-36-0]

MF C21H27N3O3S.HCl
MW 437.98

Purity: 98%
Optical purity: Optically pure
Soluble in DMSO

Sonepiprazole hydrochloride

Description

Selective dopamine D4 antagonist; Displayed high affinity (Ki = 10 nM) and selectivity for the D4 receptor expressed in clonal cell lines, lacking measurable affinity for other dopamine receptors, and noradrenalin, serotonin and histamine receptor families (Ki > 2000 nM)

PA Broderick et al. Clozapine, haloperidol, and the D4 antagonist PNU-101387G: in vivo effects on mesocortical, mesolimbic, and nigrostriatal dopamine and serotonin release. J. Neural. Transm. 1998, 105(6-7), 749-767.?

KM Merchant et al. Pharmacological characterization of U-101387, a dopamine D4 receptor selective antagonist. J. Pharmacol. Exp. Ther. 1996, 279(3), 1392-1403.?

Certificate of Analysis
Material Safety Data Sheet

CNS D4 A17 Pfizer Licensed Products

Selective dopamine D4 antagonist

Chemical name

(S)-4-(4-(2-(isochroman-1-yl)ethyl)piperazin-1-yl)benzenesulfonamide hydrochloride

Source information

Pfizer compound; Sold for research purposes under agreement from Pfizer Inc.

Parent CAS No.

[170858-33-0]

產(chǎn)品資料

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