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產(chǎn)品名稱

NS 30678 hydrochloride

產(chǎn)品貨號

Axon 1742 CAS [1193707-19-5] MF C12H16ClNO4S.HClMW 342.24 Purity: 99% Optical purity: Optically pure Soluble in water and DMSO Description Dopamine D2 receptor ligand with surmountable/competitive-like D2 antagonist properties (Ki and IC50 values of value 9.7 nM and 7 nM, repectively in HEK-hD2L-Gαqi5 cells), equipotent to Haloperidol and Risperidone (Axon 1454). NS30678 shows rapid recovery and dopamine responsiveness within 5 min after administration. References Certificates Categories Extra info T. Dyhring et al. The dopaminergic stabilizers pridopidine (ACR16) and (-)-OSU6162 display dopamine D(2) receptor antagonism and fast receptor dissociation properties. Eur J Pharmacol. 2010 Feb 25;628(1-3):19-26. ? K. Sahlholm et al. Typical and atypical antipsychotics do not differ markedly in their reversibility of antagonism of the dopamine D2 receptor. Int J Neuropsychopharmacol. 2014 Jan;17(1):149-55. Certificate of Analysis Material Safety Data Sheet CNS D2 A17 D2 ligand with surmountable/competitive-like D2 antagonist properties Chemical name (S)-N-((5-chloro-7-(methylsulfonyl)-2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)ethanamine hydrochloride Parent CAS No. [1193707-15-1] Order Size Unit Price Stock 2 mg €115.00 In Stock

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現(xiàn)貨詢價，電話：010-67529703

產(chǎn)品規(guī)格

產(chǎn)品品牌

axonmedchem

產(chǎn)品概述

產(chǎn)品詳情

NS 30678 hydrochloride

Based on 14 reference(s) in Google Scholar 8 10 14

Axon 1742

CAS [1193707-19-5]

MF C12H16ClNO4S.HCl
MW 342.24

Purity: 99%
Optical purity: Optically pure
Soluble in water and DMSO

NS 30678 hydrochloride

Description

Dopamine D2 receptor ligand with surmountable/competitive-like D2 antagonist properties (Ki and IC50 values of value 9.7 nM and 7 nM, repectively in HEK-hD2L-Gαqi5 cells), equipotent to Haloperidol and Risperidone (Axon 1454). NS30678 shows rapid recovery and dopamine responsiveness within 5 min after administration.

T. Dyhring et al. The dopaminergic stabilizers pridopidine (ACR16) and (-)-OSU6162 display dopamine D(2) receptor antagonism and fast receptor dissociation properties. Eur J Pharmacol. 2010 Feb 25;628(1-3):19-26.

K. Sahlholm et al. Typical and atypical antipsychotics do not differ markedly in their reversibility of antagonism of the dopamine D2 receptor. Int J Neuropsychopharmacol. 2014 Jan;17(1):149-55.

Certificate of Analysis
Material Safety Data Sheet

CNS D2 A17

D2 ligand with surmountable/competitive-like D2 antagonist properties

Chemical name

(S)-N-((5-chloro-7-(methylsulfonyl)-2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)ethanamine hydrochloride

Parent CAS No.

[1193707-15-1]

產(chǎn)品資料

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