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產(chǎn)品名稱(chēng)

Bortezomib - PS 341

產(chǎn)品貨號(hào)

Axon 1810 CAS [179324-69-7] MF C19H25BN4O4MW 384.24 Purity: 99% Optical purity: Optically pure Soluble in DMSO Description Highly selective and reversible inhibitor of the 26S proteasome; a chemotherapy agent used in the treatment of multiple myeloma; shown to have anti-tumor activity in B cell malignancies References Certificates Categories Extra info P Bonvini?et al.?Bortezomib-mediated 26S proteasome inhibition causes cell-cycle arrest and induces apoptosis in CD-30+ anaplastic large cell lymphoma. Leukemia 2007, 21(4), 838–842. ? S Williams et al.?Differential effects of the proteasome inhibitor bortezomib on apoptosis and angiogenesis in human prostate tumor xenografts.?Mol. Cancer Ther. 2003, 2, 835-843. ? Y Ling et al.?Mechanisms of Proteasome Inhibitor PS-341-induced G2-M-Phase Arrest and Apoptosis in Human Non-Small Cell Lung Cancer Cell Lines. Clin. Cancer Res. 2003, 9,?1145-1154. ? A?Corso et al. Bortezomib plus dexamethasone can improve stem cell collection and overcome the need for additional chemotherapy before autologous transplant in patients with myeloma. Leukemia & Lymphoma 2010, 51(2), 236-242. Certificate of Analysis Material Safety Data Sheet Cell Signaling & Oncology Proteasome 26S Ubiquitin EC 3.4 Inhibitor of 26S proteasome Chemical name (R)-3-methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butan-2-ylboronic acid Parent CAS No. [179324-69-7] Order Size Unit Price Stock 5 mg €85.00 In Stock

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現(xiàn)貨詢(xún)價(jià)，電話(huà)：010-67529703

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axonmedchem

產(chǎn)品概述

產(chǎn)品詳情

Bortezomib - PS 341

Based on 8 reference(s) in Google Scholar 9 10 8

Axon 1810

CAS [179324-69-7]

MF C19H25BN4O4
MW 384.24

Purity: 99%
Optical purity: Optically pure
Soluble in DMSO

Bortezomib

Description

Highly selective and reversible inhibitor of the 26S proteasome; a chemotherapy agent used in the treatment of multiple myeloma; shown to have anti-tumor activity in B cell malignancies

P Bonvini?et al.?Bortezomib-mediated 26S proteasome inhibition causes cell-cycle arrest and induces apoptosis in CD-30+ anaplastic large cell lymphoma. Leukemia 2007, 21(4), 838–842.

S Williams et al.?Differential effects of the proteasome inhibitor bortezomib on apoptosis and angiogenesis in human prostate tumor xenografts.?Mol. Cancer Ther. 2003, 2, 835-843.

Y Ling et al.?Mechanisms of Proteasome Inhibitor PS-341-induced G2-M-Phase Arrest and Apoptosis in Human Non-Small Cell Lung Cancer Cell Lines. Clin. Cancer Res. 2003, 9,?1145-1154.

A?Corso et al. Bortezomib plus dexamethasone can improve stem cell collection and overcome the need for additional chemotherapy before autologous transplant in patients with myeloma. Leukemia & Lymphoma 2010, 51(2), 236-242.

Certificate of Analysis
Material Safety Data Sheet

Cell Signaling & Oncology Proteasome 26S Ubiquitin EC 3.4

Inhibitor of 26S proteasome

Chemical name

(R)-3-methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butan-2-ylboronic acid

Parent CAS No.

[179324-69-7]

產(chǎn)品資料

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