| 產(chǎn)品名稱 | Eact |
| 產(chǎn)品貨號(hào) | Axon 2576 CAS [461000-66-8] MF C22H24N2O5SMW 428.50 Purity: 100% Soluble in DMSO Description Strong activator of TMEM16A (ANO1; calcium activated chloride channel;CaCC) without elevating cytoplasmic Ca2+, producing outwardly rectifying currents (EC50 value 3 μM). Eact increases secretion by submucosal glands, as well as by airway surface cells exposed to a proinflammatory milieu; may be useful for treatment of cystic fibrosis (CF), dry mouth, and dry eye syndromes, and motility disorders of the gastrointestinal tract. KEYWORDS:?Eact | supplier | TMEM16A activator | CAS [461000-66-8] | Chloride | ANO1 | calcium activated chloride channel | CaCC | Ion Channel | rectifying current | secretion | cystic fibrosis | CF | dry | motility disorder | gastrointestinal tract |
| 產(chǎn)品價(jià)格 | 現(xiàn)貨詢價(jià)，電話：010-67529703 |
| 產(chǎn)品規(guī)格 | |
| 產(chǎn)品品牌 | axonmedchem |
| 產(chǎn)品概述 | |
| 產(chǎn)品詳情 |
EactAxon 2576 CAS [461000-66-8] MF C22H24N2O5S
DescriptionStrong activator of TMEM16A (ANO1; calcium activated chloride channel;CaCC) without elevating cytoplasmic Ca2+, producing outwardly rectifying currents (EC50 value 3 μM). Eact increases secretion by submucosal glands, as well as by airway surface cells exposed to a proinflammatory milieu; may be useful for treatment of cystic fibrosis (CF), dry mouth, and dry eye syndromes, and motility disorders of the gastrointestinal tract. KEYWORDS:?Eact | supplier | TMEM16A activator | CAS [461000-66-8] | Chloride | ANO1 | calcium activated chloride channel | CaCC | Ion Channel | rectifying current | secretion | cystic fibrosis | CF | dry | motility disorder | gastrointestinal tract
Activator of TMEM16A (ANO1) without elevating cytoplasmic Ca2+
Chemical name3,4,5-trimethoxy-N-(2-methoxyethyl)-N-(4-phenylthiazol-2-yl)benzamide Parent CAS No.[461000-66-8] |
| 產(chǎn)品資料 |
