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        產品名稱 SC 79
        產品貨號 Axon 2507 CAS [305834-79-1] MF C17H17ClN2O5MW 364.78 Purity: 98% Soluble in DMSO Description Unique specific activator of cytosolic Akt (PKB) with the potential to recapitulate the primary cellular function of Akt signaling in a hippocampal neuronal culture system and a mouse model for ischemic stroke, resulting in augmented neuronal survival. Paradoxically, SC 79 suppressed PH-Akt-GFP plasma membrane translocation. Close analogue of HA 14-1 (Axon 2007), a Bcl-2 antagonist (IC50 value 9 μM). KEYWORDS: SC 79 | supplier | Akt activator | SC79 |CAS [305834-79-1] | Phosphatidylinositol | Akt | Activator | PKB | cytosolic | phosphorylation | ischemia | neuronal death | stroke | Bcl-2 | HA14-1 | plecstrin homolog | translocation
        產品價格 現貨詢價,電話:010-67529703
        產品規(guī)格
        產品品牌 axonmedchem
        產品概述
        產品詳情

        SC 79

        Based on 26 publications in PubMed 10 10 26

        Axon 2507

        CAS [305834-79-1]

        MF C17H17ClN2O5
        MW 364.78

        • Purity: 98%
        • Soluble in DMSO

        SC 79

        Description

        Unique specific activator of cytosolic Akt (PKB) with the potential to recapitulate the primary cellular function of Akt signaling in a hippocampal neuronal culture system and a mouse model for ischemic stroke, resulting in augmented neuronal survival. Paradoxically, SC 79 suppressed PH-Akt-GFP plasma membrane translocation.

        Close analogue of HA 14-1 (Axon 2007), a Bcl-2 antagonist (IC50 value 9 μM).

        KEYWORDS: SC 79 | supplier | Akt activator | SC79 |CAS [305834-79-1] | Phosphatidylinositol | Akt | Activator | PKB | cytosolic | phosphorylation | ischemia | neuronal death | stroke | Bcl-2 | HA14-1 | plecstrin homolog | translocation

        產品資料
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