| 產(chǎn)品名稱 | GDC 0879 |
| 產(chǎn)品貨號(hào) | Axon 1459 CAS [905281-76-7] MF C19H18N4O2MW 334.37 Purity: 99% Soluble in DMSO Description Selective inhibitor of protein kinase, targeting B-Raf (V600E) References Certificates Categories Extra info KP Hoeflich et al. Antitumor efficacy of the novel RAF inhibitor GDC-0879 is predicted by BRAFV600E mutational status and sustained extracellular signal-regulated kinase/MAPK pathway suppression. Cancer Res. 2009, 69(7), 3042-3051. ? H Wong et al. Pharmacodynamics of 2-[4-[(1E)-1-(hydroxyimino)-2,3-dihydro-1H-inden-5-yl]-3- (pyridine-4-yl)-1H-pyrazol-1-yl]ethan-1-ol (GDC-0879), a potent and selective B-Raf kinase inhibitor. J. Pharmacol. Exp. Ther. 2009, 329(1), 360-367. Certificate of Analysis Material Safety Data Sheet Cell Signaling & Oncology MAPK EC 2.7.11.1 RAF B-Raf protein kinase inhibitor Chemical name 5-[1-(2-Hydroxy-ethyl)-3-pyridin-4-yl-1H-pyrazol-4-yl]-indan-1-one oxime Parent CAS No. [905281-76-7] Order Size Unit Price Stock 2 mg €70.00 In Stock |
| 產(chǎn)品價(jià)格 | 現(xiàn)貨詢價(jià)，電話：010-67529703 |
| 產(chǎn)品規(guī)格 | |
| 產(chǎn)品品牌 | axonmedchem |
| 產(chǎn)品概述 | |
| 產(chǎn)品詳情 |
GDC 0879Axon 1459 CAS [905281-76-7] MF C19H18N4O2
Description
Selective inhibitor of protein kinase, targeting B-Raf (V600E)
B-Raf protein kinase inhibitor
Chemical name5-[1-(2-Hydroxy-ethyl)-3-pyridin-4-yl-1H-pyrazol-4-yl]-indan-1-one oxime Parent CAS No.[905281-76-7] |
| 產(chǎn)品資料 |
