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產(chǎn)品名稱

BIRB 796 - BIRB 0796 | Doramapimod

產(chǎn)品貨號(hào)

Axon 1358 CAS [285983-48-4] MF C31H37N5O3MW 527.66 Purity: 99% Soluble in 0.1N HCl(aq) and DMSO Description Small molecule inhibitor of p38 mitogen-activated protein (MAP) kinase (MAPK); more potent than SB 203580 (Axon 1363)?on p38α and p38β MAPKs; potential agent for the treatment of inflammatory diseases *Promotion

產(chǎn)品價(jià)格

現(xiàn)貨詢價(jià)，電話：010-67529703

產(chǎn)品規(guī)格

產(chǎn)品品牌

axonmedchem

產(chǎn)品概述

產(chǎn)品詳情

BIRB 796 - BIRB 0796 | Doramapimod

Based on 173 publications in PubMed 10 10 173

Axon 1358

CAS [285983-48-4]

MF C31H37N5O3
MW 527.66

Purity: 99%
Soluble in 0.1N HCl(aq) and DMSO

BIRB 796

Description

Small molecule inhibitor of p38 mitogen-activated protein (MAP) kinase (MAPK); more potent than SB 203580 (Axon 1363)?on p38α and p38β MAPKs; potential agent for the treatment of inflammatory diseases

*Promotion: BIRB 796 is also part of Inhibitor Set(s):

Axon 5010

C Pargellis et al. Inhibition of p38 MAP kinase by utilizing a novel allosteric binding site. Nat. Struct. Biol. 2002, 9, 268-272.

Y Kuma et al. BIRB796 inhibits all p38 MAPK isoforms in vitro and in vivo. J. Boil. Chem. 2005, 280, 19472-19479.

J Bain et al. The selectivity of protein kinase inhibitors: a further update.Biochem J.?2007,?408, 297–315.

List of publications using BIRB 796 - Doramapimod (Axon 1358) purchased from Axon Medchem

Certificate of Analysis
Material Safety Data Sheet

Cell Signaling & Oncology Pain & Inflammation MAPK (p38) MAPK EC 2.7.11.24

MAPK inhibitor (p38 specific)

Chemical name

1-(5-tert-Butyl-2-p-tolyl-2H-pyrazol-3-yl)-3-[4-(2-morpholin-4-yl-ethoxy)-naphthalen-1-yl]-urea

Parent CAS No.

[285983-48-4]

產(chǎn)品資料

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