| 產(chǎn)品名稱 | Vercirnon - GSK-1605786 | CCX282-B | Traficet-EN |
| 產(chǎn)品貨號(hào) | Axon 2685 CAS [698394-73-9] MF C22H21ClN2O4SMW 444.93 Purity: 100% Soluble in DMSO Description Vercirnon is an orally bioavailable selective antagonist of the CCR9 chemokine receptor (IC50 values 5.4 nM and 3.4 nM for CCR9-mediated Ca2+ mobilization and chemotaxis on Molt-4 cells, respectively). Based on studies of the crystal structure, vercirnon binds to the intracellular side of the receptor, exerting allosteric antagonism and preventing G-protein coupling. Vercirnon was developed for treatment of inflammatory bowel disease, including Crohn's disease and celiac disease. KEYWORDS: Vercirnon | supplier | CCR9 antagonist | GSK-1605786 | CCX282-B | Traficet-EN | GSK1605786 | GSK 1605786 | CCX282B | CCX282 B | Traficet EN | CAS [698394-73-9] | ?Chemokine | Chemokine | Antagonist | Receptors | Coeliac disease | Crohn's disease | Coeliac | Crohn |
| 產(chǎn)品價(jià)格 | 現(xiàn)貨詢價(jià)，電話：010-67529703 |
| 產(chǎn)品規(guī)格 | |
| 產(chǎn)品品牌 | axonmedchem |
| 產(chǎn)品概述 | |
| 產(chǎn)品詳情 |
Vercirnon - GSK-1605786 | CCX282-B | Traficet-ENAxon 2685 CAS [698394-73-9] MF C22H21ClN2O4S
DescriptionVercirnon is an orally bioavailable selective antagonist of the CCR9 chemokine receptor (IC50 values 5.4 nM and 3.4 nM for CCR9-mediated Ca2+ mobilization and chemotaxis on Molt-4 cells, respectively). Based on studies of the crystal structure, vercirnon binds to the intracellular side of the receptor, exerting allosteric antagonism and preventing G-protein coupling. Vercirnon was developed for treatment of inflammatory bowel disease, including Crohn's disease and celiac disease. KEYWORDS: Vercirnon | supplier | CCR9 antagonist | GSK-1605786 | CCX282-B | Traficet-EN | GSK1605786 | GSK 1605786 | CCX282B | CCX282 B | Traficet EN | CAS [698394-73-9] | ?Chemokine | Chemokine | Antagonist | Receptors | Coeliac disease | Crohn's disease | Coeliac | Crohn
CCR9 antagonist
Chemical name4-(2-(4-Tert-butylphenylsulfonamido)-5-chlorobenzoyl)pyridine 1-oxide Parent CAS No.[698394-73-9] |
| 產(chǎn)品資料 |
