<button id="eiezk"><video id="eiezk"></video></button>

產(chǎn)品名稱

CP 31398

產(chǎn)品貨號(hào)

Axon 2879 CAS [1217195-61-3] MF C22H28Cl2N4OMW 435.39 Purity: 98% Soluble in water and DMSO Description CP 31398 stabilizes the core domain of the tumour suppressor p53 in vitro and is an effective anti-cancer drug by virtue of rescuing destabilized mutants of p53. Moreover, CP 31398 can induce apoptosis of human cancer cells. KEYWORDS: CP 31398 | supplier | p53 stabilizer | CP31398 | CP-31398 | CAS [1217195-61-3] | [259199-65-0] | Non Selective | p53 | Stabilizer | Transcription Factors | Apoptosis

產(chǎn)品價(jià)格

現(xiàn)貨詢價(jià)，電話：010-67529703

產(chǎn)品規(guī)格

產(chǎn)品品牌

axonmedchem

產(chǎn)品概述

產(chǎn)品詳情

CP 31398

Based on 90 reference(s) in Google Scholar 8 10 90

Axon 2879

CAS [1217195-61-3]

MF C22H28Cl2N4O
MW 435.39

Purity: 98%
Soluble in water and DMSO

CP 31398

Description

CP 31398 stabilizes the core domain of the tumour suppressor p53 in vitro and is an effective anti-cancer drug by virtue of rescuing destabilized mutants of p53. Moreover, CP 31398 can induce apoptosis of human cancer cells.

KEYWORDS: CP 31398 | supplier | p53 stabilizer | CP31398 | CP-31398 | CAS [1217195-61-3] | [259199-65-0] | Non Selective | p53 | Stabilizer | Transcription Factors | Apoptosis

BA Foster et al. Pharmacological rescue of mutant p53 conformation and function. Science. 1999 Dec 24;286(5449):2507-10.

TM Rippin et al. Characterization of the p53-rescue drug CP-31398 in vitro and in living cells. Oncogene. 2002 Mar 28;21(14):2119-29.

R Takimoto et al. The mutant p53-conformation modifying drug, CP-31398, can induce apoptosis of human cancer cells and can stabilize wild-type p53 protein. Cancer Biol Ther. 2002 Jan-Feb;1(1):47-55.

Certificate of Analysis
Material Safety Data Sheet

Apoptosis Cell Cycle Regulation Cell Signaling & Oncology Stem Cell p53 Transcription Factors DNA-damage Response Ubiquitin TF class 4.3.1

Stabilizer of p53 and inducer of apoptosis

Chemical name

(E)-N1-(2-(4-methoxystyryl)quinazolin-4-yl)-N3,N3-dimethylpropane-1,3-diamine dihydrochloride

Parent CAS No.

[259199-65-0]

產(chǎn)品資料

<button id="eiezk"><video id="eiezk"></video></button>