| 產(chǎn)品名稱 | PF 04981517 - CYP3cide | PF 4981517 |
| 產(chǎn)品貨號(hào) | Axon 2026 CAS [1390637-82-7] MF C26H32N8MW 456.59 Purity: 98% Optical purity: Optically pure Soluble in 0.1N HCl(aq) and DMSO Description Potent and selective inhibitor of Cytochrome P450 3A4 (CYP3A4) with IC50 value of 30 nM; inactivates human CYP3A4 in an efficient and time-dependent manner References Certificates Categories Extra info RL Walksky et al. Selective mechanism-based inactivation of CYP3A4 by CYP3cide (PF-04981517) and its utility as an in vitro tool for delineating the relative roles of CYP3A4 versus CYP3A5 in (...). Drug Metab. Dispos. 2012, 40(9), 1686-1697. ?? Certificate of Analysis Material Safety Data Sheet Cell Signaling & Oncology Diabetes & Metabolism EC 1.14.13.97 Cytochrome P450 Pfizer Licensed Products Inhibitor of Cytochrome P450 3A4 (CYP3A4) Chemical name (S)-1-methyl-3-(1-methyl-5-p-tolyl-1H-pyrazol-4-yl)-4-(3-(piperidin-1-yl)pyrrolidin-1-yl)-1H-pyrazolo[3,4-d]pyrimidine Source information Pfizer compound; Sold for research purposes under agreement from Pfizer Inc. Parent CAS No. [1390637-82-7] Order Size Unit Price Stock 10 mg €110.00 In Stock |
| 產(chǎn)品價(jià)格 | 現(xiàn)貨詢價(jià)，電話：010-67529703 |
| 產(chǎn)品規(guī)格 | |
| 產(chǎn)品品牌 | axonmedchem |
| 產(chǎn)品概述 | |
| 產(chǎn)品詳情 |
PF 04981517 - CYP3cide | PF 4981517Axon 2026 CAS [1390637-82-7] MF C26H32N8
Description
Potent and selective inhibitor of Cytochrome P450 3A4 (CYP3A4) with IC50 value of 30 nM; inactivates human CYP3A4 in an efficient and time-dependent manner
Inhibitor of Cytochrome P450 3A4 (CYP3A4)
Chemical name(S)-1-methyl-3-(1-methyl-5-p-tolyl-1H-pyrazol-4-yl)-4-(3-(piperidin-1-yl)pyrrolidin-1-yl)-1H-pyrazolo[3,4-d]pyrimidine Source informationPfizer compound; Sold for research purposes under agreement from Pfizer Inc.Parent CAS No.[1390637-82-7] |
| 產(chǎn)品資料 |
