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產品名稱

MG 149

產品貨號

Axon 1785 CAS [1243583-85-8] MF C22H28O3MW 340.46 Purity: 99% Soluble in DMSO Description A novel anacardic acid analog; potent and selective inhibitor of the MYST family (Tip60 and MOZ) of histone acetyltransferase (HAT). In addition, it effectively inhibits acetyltransferase activity of HeLa cells nuclear extracts.*Sold in collaboration with RuG (University of Groningen)? KEYWORDS:?MG 149 | supplier | Tip60 HAT inhibitor | MG149 | MG-149 | CAS [1243583-85-8] | Histone | MYST family | MOZ | acetyltransferase | anacardic acid | inflammation

產品價格

現(xiàn)貨詢價，電話：010-67529703

產品規(guī)格

產品品牌

axonmedchem

產品概述

產品詳情

MG 149

Based on 14 reference(s) in Google Scholar 10 10 14

Axon 1785

CAS [1243583-85-8]

MF C22H28O3
MW 340.46

Purity: 99%
Soluble in DMSO

MG 149

Description

A novel anacardic acid analog; potent and selective inhibitor of the MYST family (Tip60 and MOZ) of histone acetyltransferase (HAT). In addition, it effectively inhibits acetyltransferase activity of HeLa cells nuclear extracts.
*Sold in collaboration with RuG (University of Groningen)?

M Ghizzoni et al. 6-alkylsalicylates are selective Tip60 inhibitors and target the acetyl-CoA binding site. Eur. J. Med. Chem. 2012, 47(1), 337-344.?

FJ Dekker et al. Small molecule inhibitors of histone acetyltransferases and deacetylases are potential drugs for inflammatory diseases. Drug Discov Today. 2014 May;19(5):654-60.

F Mo et al. Acetylation of Aurora B by TIP60 ensures accurate chromosomal segregation. Nat Chem Biol. 2016 Apr;12(4):226-32.

S Cregan et al. KAT5 (Tip60) is a potential therapeutic target in malignant pleural mesothelioma. Int J Oncol. 2016 Mar;48(3):1290-6.

List of publications utilizing MG 149 (Axon 1785) purchased from Axon Medchem

Certificate of Analysis
Material Safety Data Sheet

Cell Signaling & Oncology Epigenetics HAT EC 2.3.1.48 RuG Collaboration Products

HAT inhibitor (Tip60 and MOZ specific)

Chemical name

2-(4-heptylphenethyl)-6-hydroxybenzoic acid

Source information

Sold in collaboration with RuG (University of Groningen)

Parent CAS No.

[1243583-85-8]

產品資料

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