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產(chǎn)品名稱

C 646

產(chǎn)品貨號(hào)

Axon 1781 CAS [328968-36-1] MF C24H19N3O6MW 445.42 Purity: 99% Moderately soluble in DMSO Description Competitive p300/CBP histone acetyltransferase (HAT) inhibitor with a Ki of 400 nM; Selective versus other acetyltransferases References Certificates Categories Extra info EM Bowers et al. Virtual ligand screening of the p300/CBP histone acetyltransferase: identification of a selective small molecule inhibitor. Chem. Biol. 2010, 17, 471-482.?[onlne] ? NY Crump et al. Dynamic acetylation of all lysine-4 trimethylated histone H3 is evolutionarily conserved and mediated by p300/CBP. Proc Natl Acad Sci U S A. 2011, 108(19), 7814-7819.? Certificate of Analysis Material Safety Data Sheet Cell Signaling & Oncology Epigenetics HAT EC 2.3.1.48 HAT inhibitor (p300/CBP selective) Chemical name 4-(4-((5-(4,5-dimethyl-2-nitrophenyl)furan-2-yl)methylene)-3-methyl-5-oxo-4,5-dihydro-1H-pyrazol-1-yl)benzoic acid Parent CAS No. [328968-36-1] Order Size Unit Price Stock 2 mg €60.00 In Stock

產(chǎn)品價(jià)格

現(xiàn)貨詢價(jià)，電話：010-67529703

產(chǎn)品規(guī)格

產(chǎn)品品牌

axonmedchem

產(chǎn)品概述

產(chǎn)品詳情

C 646

Based on 12 reference(s) in Google Scholar 9 10 12

Axon 1781

CAS [328968-36-1]

MF C24H19N3O6
MW 445.42

Purity: 99%
Moderately soluble in DMSO

C 646

Description

Competitive p300/CBP histone acetyltransferase (HAT) inhibitor with a Ki of 400 nM; Selective versus other acetyltransferases

EM Bowers et al. Virtual ligand screening of the p300/CBP histone acetyltransferase: identification of a selective small molecule inhibitor. Chem. Biol. 2010, 17, 471-482.?[onlne]

NY Crump et al. Dynamic acetylation of all lysine-4 trimethylated histone H3 is evolutionarily conserved and mediated by p300/CBP. Proc Natl Acad Sci U S A. 2011, 108(19), 7814-7819.?

Certificate of Analysis
Material Safety Data Sheet

Cell Signaling & Oncology Epigenetics HAT EC 2.3.1.48

HAT inhibitor (p300/CBP selective)

Chemical name

4-(4-((5-(4,5-dimethyl-2-nitrophenyl)furan-2-yl)methylene)-3-methyl-5-oxo-4,5-dihydro-1H-pyrazol-1-yl)benzoic acid

Parent CAS No.

[328968-36-1]

產(chǎn)品資料

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