| 產(chǎn)品名稱 | T0901317 |
| 產(chǎn)品貨號 | Axon 2754 CAS [293754-55-9] MF C17H12F9NO3SMW 481.33 Purity: 98% Soluble in DMSO Description T0901317 is selective liver X receptor (LXR) agonist (EC50 value of 20 nM). Oral administration of T0901317 to mice and hamsters showed that LXR activated the coordinate expression of major fatty acid biosynthetic genes (lipogenesis) and increased plasma triglyceride and phospholipid levels in both species. Complementary studies in cell culture and animals suggested that the increase in plasma lipids occurs via LXR-mediated induction of the sterol regulatory element-binding protein 1 (SREBP-1) lipogenic program. KEYWORDS: T0901317 | supplier | LXR agonist | T 0901317 | T-0901317 | CAS [293754-55-9] | Metabolism | LXR | Agonist | Receptors | Liver X Receptor | Lipogenesis |
| 產(chǎn)品價格 | 現(xiàn)貨詢價，電話：010-67529703 |
| 產(chǎn)品規(guī)格 | |
| 產(chǎn)品品牌 | axonmedchem |
| 產(chǎn)品概述 | |
| 產(chǎn)品詳情 |
T0901317Axon 2754 CAS [293754-55-9] MF C17H12F9NO3S
DescriptionT0901317 is selective liver X receptor (LXR) agonist (EC50 value of 20 nM). Oral administration of T0901317 to mice and hamsters showed that LXR activated the coordinate expression of major fatty acid biosynthetic genes (lipogenesis) and increased plasma triglyceride and phospholipid levels in both species. Complementary studies in cell culture and animals suggested that the increase in plasma lipids occurs via LXR-mediated induction of the sterol regulatory element-binding protein 1 (SREBP-1) lipogenic program. KEYWORDS: T0901317 | supplier | LXR agonist | T 0901317 | T-0901317 | CAS [293754-55-9] | Metabolism | LXR | Agonist | Receptors | Liver X Receptor | Lipogenesis
Liver X receptor (LXR) agonist
Chemical nameN-(4-(1,1,1,3,3,3-Hexafluoro-2-hydroxypropan-2-yl)phenyl)-N-(2,2,2-trifluoroethyl)benzenesulfonamide Parent CAS No.[293754-55-9] |
| 產(chǎn)品資料 |
