| 產(chǎn)品名稱 | WYE 672 |
| 產(chǎn)品貨號 | Axon 1991 CAS [1221265-37-7] MF C23H17F3N2O2SMW 442.45 Purity: 99% Soluble in DMSO Description A tissue selective liver X receptor (LXR) agonist; WYE672 showed potent binding affinity to LXRβ (IC50 = 53 nM), it had little binding affinity for LXRα (IC50 >1.0 μM) References Certificates Categories Extra info B Hu et al. Identification of phenylsulfone-substituted quinoxaline (WYE-672) as a tissue selective liver X-receptor (LXR) agonist. J. Med. Chem. 2010, 53(8), 3296-3304.? ? T Jakobsson et al. Liver X receptor biology and pharmacology: new pathways, challenges and opportunities. Trends Pharmacol Sci. 2012, 33(7), 394-404. Certificate of Analysis Material Safety Data Sheet Diabetes & Metabolism NR1H LXR Liver X receptor (LXR) agonist Chemical name 3-methyl-2-(3'-(methylsulfonyl)biphenyl-4-yl)-5-(trifluoromethyl)quinoxaline Parent CAS No. [1221265-37-7] Order Size Unit Price Stock 10 mg €125.00 In Stock |
| 產(chǎn)品價格 | 現(xiàn)貨詢價，電話：010-67529703 |
| 產(chǎn)品規(guī)格 | |
| 產(chǎn)品品牌 | axonmedchem |
| 產(chǎn)品概述 | |
| 產(chǎn)品詳情 |
WYE 672Axon 1991 CAS [1221265-37-7] MF C23H17F3N2O2S
Description
A tissue selective liver X receptor (LXR) agonist; WYE672 showed potent binding affinity to LXRβ (IC50 = 53 nM), it had little binding affinity for LXRα (IC50 >1.0 μM)
Liver X receptor (LXR) agonist
Chemical name3-methyl-2-(3'-(methylsulfonyl)biphenyl-4-yl)-5-(trifluoromethyl)quinoxaline Parent CAS No.[1221265-37-7] |
| 產(chǎn)品資料 |
