| 產(chǎn)品名稱 | SR 9243 |
| 產(chǎn)品貨號(hào) | Axon 2598 CAS [1613028-81-1] MF C31H32BrNO4S2MW 626.62 Purity: 99% Soluble in DMSO Description LXR inverse agonist that induces LXR-corepressor interaction inhibiting the Warburg effect and lipogenesis in cancer cells by reducing glycolytic and lipogenic gene expression. SR 9243 induced apoptosis in tumors without inducing weight loss, hepatotoxicity, or inflammation. Moreover, SR 9243 may mediate tumor ‘‘unmasking’’ via downregulation of the immune-suppressive effects of LXR ligands within the tumor microenvironment. Close analogue of GSK 2033 (Axon 2363) KEYWORDS: SR 9243 | supplier | LXR inverse agonist | SR9243 | CAS [1613028-81-1] | Metabolism | LXR | Inverse agonist | nuclear | Receptors | NR1H | Warburg effect | lipogenesis | cancer cells | glycolytic | lipogenic | gene expression | apoptosis | tumor unmasking |
| 產(chǎn)品價(jià)格 | 現(xiàn)貨詢價(jià)，電話：010-67529703 |
| 產(chǎn)品規(guī)格 | |
| 產(chǎn)品品牌 | axonmedchem |
| 產(chǎn)品概述 | |
| 產(chǎn)品詳情 |
SR 9243Axon 2598 CAS [1613028-81-1] MF C31H32BrNO4S2
DescriptionLXR inverse agonist that induces LXR-corepressor interaction inhibiting the Warburg effect and lipogenesis in cancer cells by reducing glycolytic and lipogenic gene expression. SR 9243 induced apoptosis in tumors without inducing weight loss, hepatotoxicity, or inflammation. Moreover, SR 9243 may mediate tumor ‘‘unmasking’’ via downregulation of the immune-suppressive effects of LXR ligands within the tumor microenvironment. KEYWORDS: SR 9243 | supplier | LXR inverse agonist | SR9243 | CAS [1613028-81-1] | Metabolism | LXR | Inverse agonist | nuclear | Receptors | NR1H | Warburg effect | lipogenesis | cancer cells | glycolytic | lipogenic | gene expression | apoptosis | tumor unmasking
LXR inverse agonist inhibiting the Warburg effect and lipogenesis in cancer cells
Chemical nameN-(3-bromophenethyl)-2,4,6-trimethyl-N-((3'-(methylsulfonyl)biphenyl-4-yl)methyl)benzenesulfonamide Parent CAS No.[1613028-81-1] |
| 產(chǎn)品資料 |
