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產(chǎn)品名稱

BAY K 8644, (S)-(-)- - BAY K8644, (-)-

產(chǎn)品貨號

產(chǎn)品價格

現(xiàn)貨詢價，電話：010-67529703

產(chǎn)品規(guī)格

產(chǎn)品品牌

axonmedchem

產(chǎn)品概述

產(chǎn)品詳情

BAY K 8644, (S)-(-)- - BAY K8644, (-)-

Based on 12 reference(s) in Google Scholar 9 10 12

Axon 1759

CAS [98625-26-4]

MF C16H15F3N2O4
MW 356.30

Purity: 99%
Optical purity: 99% ee
Soluble in DMSO and Ethanol

BAY K 8644, (S)-(-)-

Description

L-type Ca2+-channel activator with positive inotropic, vasoconstrictive and behavioral effects in vivo. The more active enantiomer (S) of Bay K8644 (Axon 1697), its opposite enantiomer, (R)-(+)-Bay-K8466 (Axon 1758) is also available.

FT Van Amsterdam et al. Stereoisomers of Bay K 8644 show opposite activities in the normal and ischemic rat heart. A comparison with nifedipine. Naunyn Schmiedebergs Arch. Pharmacol. 1989, 339, 647-652.

J Ferrante et al. Binding of a 14-dihydropyridine calcium channel activator (?)-S-Bay K 8644 to cardiac preparations. Biochem. Biophys. Res. Commun. 1989, 158, 149-154.

M Sekiguchi-Tonosaki et al. Acetylcholine Induces Ca2+ Signaling In Chicken Retinal Pigmented Epithelial Cells During Dedifferentiation. Am. J. Physiol. Cell Physiol. 2009, 296, C1195-206.

Certificate of Analysis
Material Safety Data Sheet

Cardiovascular Cell Signaling & Oncology CNS Pain & Inflammation Stem Cell Non Selective L-Type

Calcium (Ca2+) channel activator (L-type voltage-gated)

Chemical name

(S)-methyl 2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-1,4-dihydropyridine-3-carboxylate

Parent CAS No.

[98625-26-4]

產(chǎn)品資料

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