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產(chǎn)品名稱

Celecoxib - SC 58635 | Celebrex | Celebra

產(chǎn)品貨號

Axon 1919 CAS [169590-42-5] MF C17H14F3N3O2SMW 381.37 Purity: 99% Soluble in DMSO Description Selective cyclooxygenase-2 (COX-2) inhibitor (IC50: 15 and 0.04 μM for COX-1 and COX-2 respectively); inhibition of COX-2 inhibits only prostaglandin synthesis without affecting thromboxane (TXA2) and thus offers no cardioprotective effects of NSAIDs, which inhibits both COX-1 and COX-2 non-selectively. References Certificates Categories Extra info TD Penning et al. Synthesis and Biological Evaluation of the 1.5 Diarylpyrazole Class of Cyclooxygenase-2 Inhibitors: Identification of 4-[5-(4-Methylphenyl)-3-(trifluoromethyl)-1H-pyrazole-(...). J. Med. Chem. 1997, 40 (9), 1347–1365. ? DL DeWitt. Cox-2-selective inhibitors: the new super aspirins. Mol. Pharmacol. 1999, 55(4), 625-631. Certificate of Analysis Material Safety Data Sheet CNS Immunology Pain & Inflammation EC 1.14.99.1 COX Pfizer Licensed Products Selective COX-2 inhibitor Chemical name 4-(5-p-tolyl-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide Source information Pfizer compound; Sold for research purposes under agreement from Pfizer Inc. Parent CAS No. [169590-42-5] Order Size Unit Price Stock 10 mg €50.00 In Stock

產(chǎn)品價格

現(xiàn)貨詢價，電話：010-67529703

產(chǎn)品規(guī)格

產(chǎn)品品牌

axonmedchem

產(chǎn)品概述

產(chǎn)品詳情

Celecoxib - SC 58635 | Celebrex | Celebra

Based on 12 reference(s) in Google Scholar 9 10 12

Axon 1919

CAS [169590-42-5]

MF C17H14F3N3O2S
MW 381.37

Purity: 99%
Soluble in DMSO

Celecoxib

Description

Selective cyclooxygenase-2 (COX-2) inhibitor (IC50: 15 and 0.04 μM for COX-1 and COX-2 respectively); inhibition of COX-2 inhibits only prostaglandin synthesis without affecting thromboxane (TXA2) and thus offers no cardioprotective effects of NSAIDs, which inhibits both COX-1 and COX-2 non-selectively.

TD Penning et al. Synthesis and Biological Evaluation of the 1.5 Diarylpyrazole Class of Cyclooxygenase-2 Inhibitors: Identification of 4-[5-(4-Methylphenyl)-3-(trifluoromethyl)-1H-pyrazole-(...). J. Med. Chem. 1997, 40 (9), 1347–1365.

DL DeWitt. Cox-2-selective inhibitors: the new super aspirins. Mol. Pharmacol. 1999, 55(4), 625-631.

Certificate of Analysis
Material Safety Data Sheet

CNS Immunology Pain & Inflammation EC 1.14.99.1 COX Pfizer Licensed Products

Selective COX-2 inhibitor

Chemical name

4-(5-p-tolyl-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide

Source information

Pfizer compound; Sold for research purposes under agreement from Pfizer Inc.

Parent CAS No.

[169590-42-5]

產(chǎn)品資料

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