<button id="eiezk"><video id="eiezk"></video></button>

產(chǎn)品名稱

ThioLox - Thiophene A9

產(chǎn)品貨號

Axon 2844 CAS [1202193-89-2] MF C15H18N2OSMW 274.38 Purity: 99% Soluble in DMSO Description Inhibitor of 15-lipoxygenase-1 (15-LOX-1) with both anti-inflammatory and neuroprotective properties (IC50 value of 12 μM). Ex vivo biological evaluation in precision-cut lung slices (PCLS) showed inhibition of pro-inflammatory gene expression and in vitro studies on neuronal HT-22 cells showed a strong protection against glutamate toxicity for this 15-LOX-1 inhibitor. KEYWORDS: Thiolox | supplier | Lipoxygenase inhibitor | CAS [1202193-89-2] | Fatty acid (Arachidonic acid) | LOX | Inhibitor | Enzymes

產(chǎn)品價(jià)格

現(xiàn)貨詢價(jià)，電話：010-67529703

產(chǎn)品規(guī)格

產(chǎn)品品牌

axonmedchem

產(chǎn)品概述

產(chǎn)品詳情

ThioLox - Thiophene A9

Based on 3 reference(s) in Google Scholar 8 10 3

Axon 2844

CAS [1202193-89-2]

MF C15H18N2OS
MW 274.38

Purity: 99%
Soluble in DMSO

ThioLox

Description

Inhibitor of 15-lipoxygenase-1 (15-LOX-1) with both anti-inflammatory and neuroprotective properties (IC50 value of 12 μM). Ex vivo biological evaluation in precision-cut lung slices (PCLS) showed inhibition of pro-inflammatory gene expression and in vitro studies on neuronal HT-22 cells showed a strong protection against glutamate toxicity for this 15-LOX-1 inhibitor.

N Eleftheriadis et al. Design of a novel thiophene inhibitor of 15-lipoxygenase-1 with both anti-inflammatory and neuroprotective properties. Eur J Med Chem. 2016 Oct 21;122:786-801.

Certificate of Analysis
Material Safety Data Sheet

Apoptosis Cardiovascular CNS Pain & Inflammation LOX EC 1.13.11.31 RuG

Inhibitor of 15-lipoxygenase-1 (15-LOX-1)

Chemical name

2-Amino-N-butyl-5-phenylthiophene-3-carboxamide

Parent CAS No.

[1202193-89-2]

產(chǎn)品資料

<button id="eiezk"><video id="eiezk"></video></button>