| 產(chǎn)品名稱 | SC 26196 - PF 06341724 |
| 產(chǎn)品貨號 | Axon 2112 CAS [218136-59-5] MF C27H29N5MW 423.55 Purity: 99% Soluble in DMSO Description Selective Δ6-desaturase inhibitor (IC50 = 0.2 μM in vitro; >100 fold selective over Δ5- and Δ9-desaturases), an enzyme essential for the synthesis of arachidonic acid. It showed anti-inflammatory effects to the same extent as indomethacin or essential fatty acid deficiency in established mouse models References Certificates Categories Extra info MG Obukowicz et al. Novel, selective delta6 or delta5 fatty acid desaturase inhibitors as antiinflammatory agents in mice. J. Pharmacol. Exp. Ther. 1998, 287(1), 157-166.? ? MB Hansen-Petrik et al. Selective inhibition of Delta-6 desaturase impedes intestinal tumorigenesis. Cancer Lett. 2002, 175(2), 157-163.? Certificate of Analysis Material Safety Data Sheet Cell Signaling & Oncology Diabetes & Metabolism Pain & Inflammation FADS2 EC 1.14.19.1 Pfizer Licensed Products Selective Δ6-desaturase inhibitor Chemical name 2,2-diphenyl-5-(4-(pyridin-3-ylmethyleneamino)piperazin-1-yl)pentanenitrile Source information Pfizer compound; Sold for research purposes under agreement from Pfizer Inc. Parent CAS No. [218136-59-5] Order Size Unit Price Stock 5 mg €85.00 In Stock |
| 產(chǎn)品價格 | 現(xiàn)貨詢價，電話：010-67529703 |
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| 產(chǎn)品品牌 | axonmedchem |
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| 產(chǎn)品詳情 |
SC 26196 - PF 06341724Axon 2112 CAS [218136-59-5] MF C27H29N5
Description
Selective Δ6-desaturase inhibitor (IC50 = 0.2 μM in vitro; >100 fold selective over Δ5- and Δ9-desaturases), an enzyme essential for the synthesis of arachidonic acid. It showed anti-inflammatory effects to the same extent as indomethacin or essential fatty acid deficiency in established mouse models
Selective Δ6-desaturase inhibitor
Chemical name2,2-diphenyl-5-(4-(pyridin-3-ylmethyleneamino)piperazin-1-yl)pentanenitrile Source informationPfizer compound; Sold for research purposes under agreement from Pfizer Inc.Parent CAS No.[218136-59-5] |
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