| 產(chǎn)品名稱 | Boc-D-FMK - Boc-Asp(OMe)-fluoromethyl ketone | BAF |
| 產(chǎn)品貨號(hào) | Axon 2158 CAS [187389-53-3] MF C11H18FNO5MW 263.26 Purity: 98% Optical purity: Optically pure Soluble in water and DMSO Description Broad spectrum caspase inhibitor. Causes concentration-dependent inhibition of only TNFα-stimulated apoptosis (IC50 value 39 μM). Boc-D-FMK could significantly promote the survival of spinal motoneurons after root avulsion in neonates, but not in adult rats. Boc-D-FMK treatment reduces acute cell death after traumatic brain injury (TBI) by inhibiting mitochondrial release of cytochrome c, possibly via a mechanism involving initiator caspases-2, and -3-like, but not -8). KEYWORS: Boc-D-FMK | supplier | Caspase inhibitor | apoptosis | TNF | boc-Aspartyl(OMe)-fluoromethylketone | BAF | traumatic | Brain injury | TBI | survival | motoneurons |
| 產(chǎn)品價(jià)格 | 現(xiàn)貨詢價(jià)，電話：010-67529703 |
| 產(chǎn)品規(guī)格 | |
| 產(chǎn)品品牌 | axonmedchem |
| 產(chǎn)品概述 | |
| 產(chǎn)品詳情 |
Boc-D-FMK - Boc-Asp(OMe)-fluoromethyl ketone | BAFAxon 2158 CAS [187389-53-3] MF C11H18FNO5
DescriptionBroad spectrum caspase inhibitor. Causes concentration-dependent inhibition of only TNFα-stimulated apoptosis (IC50 value 39 μM). Boc-D-FMK could significantly promote the survival of spinal motoneurons after root avulsion in neonates, but not in adult rats. Boc-D-FMK treatment reduces acute cell death after traumatic brain injury (TBI) by inhibiting mitochondrial release of cytochrome c, possibly via a mechanism involving initiator caspases-2, and -3-like, but not -8). KEYWORS: Boc-D-FMK | supplier | Caspase inhibitor | apoptosis | TNF | boc-Aspartyl(OMe)-fluoromethylketone | BAF | traumatic | Brain injury | TBI | survival | motoneurons
Broad spectrum caspase inhibitor
Chemical name(S)-methyl 3-(tert-butoxycarbonylamino)-5-fluoro-4-oxopentanoate Parent CAS No.[187389-53-3] |
| 產(chǎn)品資料 |
