| 產(chǎn)品名稱 | NHI 2 |
| 產(chǎn)品貨號 | Axon 2450 CAS [1269802-97-2] MF C17H12F3NO3MW 335.28 Purity: 99% Soluble in DMSO Description Selective cell membrane permeable inhibitor of human lactate dehydrogenase isoform A (LDH-A; IC50 values 14.7 μM and 55.8 μM in a NADH competition assay for LDH-A and LDH-B, respectively). NHI-2 caused 87% LDH-A inhibition at 125 μM (with minimal activity (11%) on LDH-B at the same concentration), exhibiting anti-proliferative activity in cancer cells. NHI 2 synergistically enhanced the activity of Gemcitabine in multiple cancer cell lines. KEYWORDS: NHI2 | supplier | LDH-A inhibitor | CAS [1269802-97-2] | Lactate | LDH | Inhibitor | pyruvate | glycolysis | dehydrogenase | anti-proliferative | cancer | cytotoxic | hypoxia | cell-cycle | apoptosis | NADH |
| 產(chǎn)品價格 | 現(xiàn)貨詢價，電話：010-67529703 |
| 產(chǎn)品規(guī)格 | |
| 產(chǎn)品品牌 | axonmedchem |
| 產(chǎn)品概述 | |
| 產(chǎn)品詳情 |
NHI 2Axon 2450 CAS [1269802-97-2] MF C17H12F3NO3
DescriptionSelective cell membrane permeable inhibitor of human lactate dehydrogenase isoform A (LDH-A; IC50 values 14.7 μM and 55.8 μM in a NADH competition assay for LDH-A and LDH-B, respectively). NHI-2 caused 87% LDH-A inhibition at 125 μM (with minimal activity (11%) on LDH-B at the same concentration), exhibiting anti-proliferative activity in cancer cells. NHI 2 synergistically enhanced the activity of Gemcitabine in multiple cancer cell lines. KEYWORDS: NHI2 | supplier | LDH-A inhibitor | CAS [1269802-97-2] | Lactate | LDH | Inhibitor | pyruvate | glycolysis | dehydrogenase | anti-proliferative | cancer | cytotoxic | hypoxia | cell-cycle | apoptosis | NADH
Selective cell membrane permeable inhibitor of human lactate dehydrogenase A
Chemical namemethyl 1-hydroxy-6-phenyl-4-(trifluoromethyl)-1H-indole-2-carboxylate Parent CAS No.[1269802-97-2] |
| 產(chǎn)品資料 |
