| 產(chǎn)品名稱 | URB602 |
| 產(chǎn)品貨號 | Axon 2696 CAS [565460-15-3] MF C19H21NO2MW 295.38 Purity: 99% Soluble in DMSO Description Non-competitive inhibitor of MAGL (monoacylglycerol lipase; IC50 values 25 μM and 17 μM for inhibition of hydrolysis of 2-oleoylglycerol (2-OG) and anandamide (AEA), respectively), lacking affinity for FAAH, diacylglycerol lipase or COX-2. URB602 blocks 2-AG hydrolysis in rat brain slices and enhances non-opioid stress-induced analgesia. Furthermore, URB602 reduced xenograft tumor volume, this effect being associated to down-regulation of VEGF and FGF-2, reduction in the number of vessels and down-regulation of cyclin D1. KEYWORDS: URB602 | supplier | MAGL inhibitor | URB 602 | URB-602 | CAS [565460-15-3] | ?2-arachidonoyl glycerol (2-AG) | MAGL | Inhibitor | Enzymes |
| 產(chǎn)品價格 | 現(xiàn)貨詢價，電話：010-67529703 |
| 產(chǎn)品規(guī)格 | |
| 產(chǎn)品品牌 | axonmedchem |
| 產(chǎn)品概述 | |
| 產(chǎn)品詳情 |
URB602Axon 2696 CAS [565460-15-3] MF C19H21NO2
DescriptionNon-competitive inhibitor of MAGL (monoacylglycerol lipase; IC50 values 25 μM and 17 μM for inhibition of hydrolysis of 2-oleoylglycerol (2-OG) and anandamide (AEA), respectively), lacking affinity for FAAH, diacylglycerol lipase or COX-2. URB602 blocks 2-AG hydrolysis in rat brain slices and enhances non-opioid stress-induced analgesia. Furthermore, URB602 reduced xenograft tumor volume, this effect being associated to down-regulation of VEGF and FGF-2, reduction in the number of vessels and down-regulation of cyclin D1. KEYWORDS: URB602 | supplier | MAGL inhibitor | URB 602 | URB-602 | CAS [565460-15-3] | ?2-arachidonoyl glycerol (2-AG) | MAGL | Inhibitor | Enzymes
Non-competitive inhibitor of MAGL
Chemical nameCyclohexyl biphenyl-3-ylcarbamate Parent CAS No.[565460-15-3] |
| 產(chǎn)品資料 |
