| 產(chǎn)品名稱 | RUSKI-201 dihydrochloride |
| 產(chǎn)品貨號 | Axon 2673 CAS [N.A.] MF C20H27N3OS.2HClMW 430.43 Purity: 98% Optical purity: Racemic Soluble in water and DMSO Description Sonic Hedgehog acyltransferase (HHAT) inhibitor (IC50 value 0.20 μM) showing no off-target cytotoxicity, and quantitative whole-proteome palmitoylation profiling with a bioorthogonal alkyne-palmitate reporter. RUSKI-201 is the optimal tool molecule currently available to study HHAT function. References Certificates Categories Extra info UR Rodgers et al. Characterization of Hedgehog Acyltransferase Inhibitors Identifies a Small Molecule Probe for Hedgehog Signaling by Cancer Cells. ACS Chem Biol. 2016 Dec 16;11(12):3256-3262. ? X Zhang et al. Development of anticancer agents targeting the Hedgehog signaling. Cell Mol Life Sci. 2017 Mar 17. Certificate of Analysis Material Safety Data Sheet Cell Signaling & Oncology CNS Stem Cell HHAT Hedgehog EC 2.3.1 Sonic HHAT inhibitor lacking off-target cytotoxicity Chemical name 2-(2-methylbutylamino)-1-(4-(6-methylpyridin-2-yl)-6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)ethanone dihydrochloride Parent CAS No. [1458031-48-5] Order Size Unit Price Stock 5 mg €135.00 In Stock |
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| 產(chǎn)品品牌 | axonmedchem |
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| 產(chǎn)品詳情 |
RUSKI-201 dihydrochlorideAxon 2673 CAS [N.A.] MF C20H27N3OS.2HCl
Description
Sonic Hedgehog acyltransferase (HHAT) inhibitor (IC50 value 0.20 μM) showing no off-target cytotoxicity, and quantitative whole-proteome palmitoylation profiling with a bioorthogonal alkyne-palmitate reporter. RUSKI-201 is the optimal tool molecule currently available to study HHAT function.
Sonic HHAT inhibitor lacking off-target cytotoxicity
Chemical name2-(2-methylbutylamino)-1-(4-(6-methylpyridin-2-yl)-6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)ethanone dihydrochloride Parent CAS No.[1458031-48-5] |
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