| 產(chǎn)品名稱 | JK184 |
| 產(chǎn)品貨號 | Axon 2654 CAS [315703-52-7] MF C19H18N4OSMW 350.44 Purity: 100% Soluble in DMSO and Ethanol Description Antagonist of Hedgehog (Hh) signaling (IC50 value of 30 nM for inhibition of Gli-dependent transcriptional activity) and a potent inhibitor of microtubule assembly that exhibits good antiproliferative activity both in vitro and in vivo. JK184 appears to act by inhibition of Adh7 (Kd value 210 nM in a assay for enzymatic oxidation of retinol). KEYWORDS:?JK184 | supplier | Hedgehog inhibitor | JK-184 | CAS [315703-52-7] | [466638-53-9] | Hedgehog | ADH | Antagonist | Hh | Smoothened | Smo | Patched | Ptch1 | Ptc | Gli | microtubules | Sonic | shh | Indian | ihh | Desert | dhh |
| 產(chǎn)品價格 | 現(xiàn)貨詢價，電話：010-67529703 |
| 產(chǎn)品規(guī)格 | |
| 產(chǎn)品品牌 | axonmedchem |
| 產(chǎn)品概述 | |
| 產(chǎn)品詳情 |
JK184Axon 2654 CAS [315703-52-7] MF C19H18N4OS
DescriptionAntagonist of Hedgehog (Hh) signaling (IC50 value of 30 nM for inhibition of Gli-dependent transcriptional activity) and a potent inhibitor of microtubule assembly that exhibits good antiproliferative activity both in vitro and in vivo. JK184 appears to act by inhibition of Adh7 (Kd value 210 nM in a assay for enzymatic oxidation of retinol). KEYWORDS:?JK184 | supplier | Hedgehog inhibitor | JK-184 | CAS [315703-52-7] | [466638-53-9] | Hedgehog | ADH | Antagonist | Hh | Smoothened | Smo | Patched | Ptch1 | Ptc | Gli | microtubules | Sonic | shh | Indian | ihh | Desert | dhh
Hedgehog (Hh) signaling pathway antagonist with antiproliferative activity
Chemical nameN-(4-ethoxyphenyl)-4-(2-methylimidazo[1,2-a]pyridin-3-yl)thiazol-2-amine Parent CAS No.[315703-52-7] |
| 產(chǎn)品資料 |
