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產(chǎn)品名稱

UK 383367

產(chǎn)品貨號

Axon 2073 CAS [348622-88-8] MF C15H24N4O4MW 324.38 Purity: 99% Soluble in DMSO Description Potent and selective inhibitor of bone morphogenetic protein 1 (BMP-1; also known as procollagen C proteinase, PCP) with IC50 values of 44 nM for BMP-1 and >10.000 nM for a range of other proteolytic matrix metalloproteinases MMP-1, 2, 3, 9, and 14. References Certificates Categories Extra info PV Fish et al. Potent and Selective Nonpeptidic Inhibitors of Procollagen C-Proteinase. J. Med. Chem. 2007, 50, 3442-3456.? ? GA Allan et al. Pharmacokinetics and metabolism of UK-383,367 in rats and dogs: a rationale for long-lived plasma radioactivity. Xenobiotica. 2006, 36, 399-418.? ? S Bailey et al. Succinyl hydroxamates as potent and selective non-peptidic inhibitors of procollagen C-proteinase: design, synthesis, and evaluation as topically applied, dermal anti-scarring agents. Bioorg. Med. Chem. Lett. 2008, 18, 6562-6567.? Certificate of Analysis Material Safety Data Sheet Angiogenesis Cell Signaling & Oncology Miscellaneous Pain & Inflammation EC 3.4.24.19 MMP Pfizer Licensed Products Inhibitor of bone morphogenetic protein 1 (BMP-1, aka PCP) Chemical name (R)-5-(6-cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-yl)-1,2,4-oxadiazole-3-carboxamide Source information Pfizer compound; Sold for research purposes under agreement from Pfizer Inc. Parent CAS No. [348622-88-8] Order Size Unit Price Stock 5 mg €80.00 In Stock

產(chǎn)品價格

現(xiàn)貨詢價，電話：010-67529703

產(chǎn)品規(guī)格

產(chǎn)品品牌

axonmedchem

產(chǎn)品概述

產(chǎn)品詳情

UK 383367

Based on 18 reference(s) in Google Scholar 9 10 18

Axon 2073

CAS [348622-88-8]

MF C15H24N4O4
MW 324.38

Purity: 99%
Soluble in DMSO

UK 383367

Description

Potent and selective inhibitor of bone morphogenetic protein 1 (BMP-1; also known as procollagen C proteinase, PCP) with IC50 values of 44 nM for BMP-1 and >10.000 nM for a range of other proteolytic matrix metalloproteinases MMP-1, 2, 3, 9, and 14.

PV Fish et al. Potent and Selective Nonpeptidic Inhibitors of Procollagen C-Proteinase. J. Med. Chem. 2007, 50, 3442-3456.?

GA Allan et al. Pharmacokinetics and metabolism of UK-383,367 in rats and dogs: a rationale for long-lived plasma radioactivity. Xenobiotica. 2006, 36, 399-418.?

S Bailey et al. Succinyl hydroxamates as potent and selective non-peptidic inhibitors of procollagen C-proteinase: design, synthesis, and evaluation as topically applied, dermal anti-scarring agents. Bioorg. Med. Chem. Lett. 2008, 18, 6562-6567.?

Certificate of Analysis
Material Safety Data Sheet

Angiogenesis Cell Signaling & Oncology Miscellaneous Pain & Inflammation EC 3.4.24.19 MMP Pfizer Licensed Products

Inhibitor of bone morphogenetic protein 1 (BMP-1, aka PCP)

Chemical name

(R)-5-(6-cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-yl)-1,2,4-oxadiazole-3-carboxamide

Source information

Pfizer compound; Sold for research purposes under agreement from Pfizer Inc.

Parent CAS No.

[348622-88-8]

產(chǎn)品資料

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