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產(chǎn)品名稱

DDR1-IN-1

產(chǎn)品貨號

Axon 2265 CAS [1449685-96-4] MF C30H31F3N4O3MW 552.59 Purity: 98% Soluble in DMSO Description Potent and selective DDR1 receptor tyrosine kinase (RTK) inhibitor (IC50 values 105 and 413 nM for DDR1 and DDR2 respectively); a useful pharmacological probe for DDR1-dependent signal transduction. References Certificates Categories Extra info H.G. Kim et al. Discovery of a potent and selective DDR1 receptor tyrosine kinase inhibitor. A.C.S. Chem. Biol. 2014, 9, 840. ? P. Canning et al. Structural mechanisms determining inhibition of the collagen receptor DDR1 by selective and multi-targeted type II kinase inhibitors. J. Mol. Biol. 2014, 426, 2457-2470. Certificate of Analysis Material Safety Data Sheet Cell Signaling & Oncology DDR1 RTK class XVI; EC 2.7.10.1 Selective DDR1 receptor tyrosine kinase (RTK) inhibitor Chemical name 4-((4-Ethylpiperazin-1-yl)methyl)-N-(4-methyl-3-(2-oxoindolin-5-yloxy)phenyl)-3-(trifluoromethyl)benzamide Parent CAS No. [1449685-96-4] Order Size Unit Price Stock 5 mg €95.00 In Stock

產(chǎn)品價(jià)格

現(xiàn)貨詢價(jià)，電話：010-67529703

產(chǎn)品規(guī)格

產(chǎn)品品牌

axonmedchem

產(chǎn)品概述

產(chǎn)品詳情

DDR1-IN-1

Based on 12 reference(s) in Google Scholar 9 10 12

Axon 2265

CAS [1449685-96-4]

MF C30H31F3N4O3
MW 552.59

Purity: 98%
Soluble in DMSO

DDR1-IN-1

Description

Potent and selective DDR1 receptor tyrosine kinase (RTK) inhibitor (IC50 values 105 and 413 nM for DDR1 and DDR2 respectively); a useful pharmacological probe for DDR1-dependent signal transduction.

H.G. Kim et al. Discovery of a potent and selective DDR1 receptor tyrosine kinase inhibitor. A.C.S. Chem. Biol. 2014, 9, 840.

P. Canning et al. Structural mechanisms determining inhibition of the collagen receptor DDR1 by selective and multi-targeted type II kinase inhibitors. J. Mol. Biol. 2014, 426, 2457-2470.

Certificate of Analysis
Material Safety Data Sheet

Cell Signaling & Oncology DDR1 RTK class XVI; EC 2.7.10.1

Selective DDR1 receptor tyrosine kinase (RTK) inhibitor

Chemical name

4-((4-Ethylpiperazin-1-yl)methyl)-N-(4-methyl-3-(2-oxoindolin-5-yloxy)phenyl)-3-(trifluoromethyl)benzamide

Parent CAS No.

[1449685-96-4]

產(chǎn)品資料

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