| 產(chǎn)品名稱 | ARQ 197 - Tivantinib |
| 產(chǎn)品貨號 | Axon 1838 CAS [905854-02-6] MF C23H19N3O2MW 369.42 Purity: 98% Soluble in DMSO Description Selective, non-ATP-competitive and orally bioavailable inhibitor of c-MET receptor tyrosine kinase (RTK) References Certificates Categories Extra info N Munshi et al. ARQ 197, a Novel and Selective Inhibitor of the Human c-Met Receptor Tyrosine Kinase with Antitumor Activity. Mol. Cancer Ther. 2010, 9, 1544-1553.? ? R Bagai et al. ARQ-197, an oral small-molecule inhibitor of c-Met for the treatment of solid tumors. IDrugs. 2010, 13(6), 404-414.? ? AA Adjei et al. Early clinical development of ARQ 197, a selective, non-ATP-competitive inhibitor targeting MET tyrosine kinase for the treatment of advanced cancers. Oncologist. 2011, 16(6), 788-799.? ? S Eathiraj et al. Discovery of a novel mode of protein kinase inhibition characterized by the mechanism of inhibition of human mesenchymal-epithelial transition factor (c-Met) protein autophosphorylation (...). J. Biol. Chem. 2011, 286(23), 20666-20676.? Certificate of Analysis Material Safety Data Sheet Cell Signaling & Oncology c-MET RTK class X; EC 2.7.10.1 c-MET tyrosine kinase Inhibitor Chemical name (3R,4R)-3-(2,3-dihydro-1H-pyrrolo[3,2,1-ij]quinolin-6-yl)-4-(1H-indol-3-yl)pyrrolidine-2,5-dione Parent CAS No. [905854-02-6] Order Size Unit Price Stock 5 mg €95.00 In Stock |
| 產(chǎn)品價格 | 現(xiàn)貨詢價，電話：010-67529703 |
| 產(chǎn)品規(guī)格 | |
| 產(chǎn)品品牌 | axonmedchem |
| 產(chǎn)品概述 | |
| 產(chǎn)品詳情 |
ARQ 197 - TivantinibAxon 1838 CAS [905854-02-6] MF C23H19N3O2
Description
Selective, non-ATP-competitive and orally bioavailable inhibitor of c-MET receptor tyrosine kinase (RTK)
c-MET tyrosine kinase Inhibitor
Chemical name(3R,4R)-3-(2,3-dihydro-1H-pyrrolo[3,2,1-ij]quinolin-6-yl)-4-(1H-indol-3-yl)pyrrolidine-2,5-dione Parent CAS No.[905854-02-6] |
| 產(chǎn)品資料 |
