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產(chǎn)品名稱(chēng)

Tucidinostat - Chidamide | HBI-8000 | CS 055 | Epidaza

產(chǎn)品貨號(hào)

Axon 2893 CAS [1616493-44-7] MF C22H19FN4O2MW 390.41 Purity: 99% Soluble in 0.1N HCl(aq) and DMSO Description Tucidinostat (Chidamide) is an orally bioavailable inhibitor of HDAC1, HDAC2, HDAC3, and HDAC10 with IC50 values of 0.095, 0.160, 0.067, 0.078 μM, respectively. Tucidinostat exhibits a significant and broad spectrum in vitro and in vivo antitumor activity, including a wide therapeutic index. Keywords: Tucidinostat | supplier | HDAC inhibitor | Chidamide | HBI-8000 | CS 055 | Epidaza | HBI8000 | HBI 8000 | CS055 | CS-055 | CAS [1616493-44-7] | Histone | HDAC | Inhibitor | Enzymes

產(chǎn)品價(jià)格

現(xiàn)貨詢(xún)價(jià)，電話(huà)：010-67529703

產(chǎn)品規(guī)格

產(chǎn)品品牌

axonmedchem

產(chǎn)品概述

產(chǎn)品詳情

Tucidinostat - Chidamide | HBI-8000 | CS 055 | Epidaza

Based on 82 reference(s) in Google Scholar 8 10 82

Axon 2893

CAS [1616493-44-7]

MF C22H19FN4O2
MW 390.41

Purity: 99%
Soluble in 0.1N HCl(aq) and DMSO

Tucidinostat

Description

Tucidinostat (Chidamide) is an orally bioavailable inhibitor of HDAC1, HDAC2, HDAC3, and HDAC10 with IC50 values of 0.095, 0.160, 0.067, 0.078 μM, respectively. Tucidinostat exhibits a significant and broad spectrum in vitro and in vivo antitumor activity, including a wide therapeutic index.

Keywords: Tucidinostat | supplier | HDAC inhibitor | Chidamide | HBI-8000 | CS 055 | Epidaza | HBI8000 | HBI 8000 | CS055 | CS-055 | CAS [1616493-44-7] | Histone | HDAC | Inhibitor | Enzymes

ZQ Ning et al. Chidamide (CS055/HBI-8000): a new histone deacetylase inhibitor of the benzamide class with antitumor activity and the ability to enhance immune cell-mediated tumor cell cytotoxicity. Cancer Chemother Pharmacol. 2012 Apr;69(4):901-9.

Certificate of Analysis
Material Safety Data Sheet

Apoptosis Cell Cycle Regulation Cell Signaling & Oncology Epigenetics DNA-damage Response EC 3.5.1.98 HDAC

Orally bioavailable HDAC inhibitor (1, 2, 3, 10 Selective)

Chemical name

(E)-N-(2-Amino-4-fluorophenyl)-4-((3-(pyridin-3-yl)acrylamido)methyl)benzamide

Parent CAS No.

[1616493-44-7]

產(chǎn)品資料

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