| 產(chǎn)品名稱 | Mocetinostat - MGCD 0103 | MG 0103 |
| 產(chǎn)品貨號(hào) | Axon 2505 CAS [726169-73-9] MF C23H20N6OMW 396.44 Purity: 99% Soluble in 0.1N HCl(aq) and DMSO Description Class I selective HDAC inhibitor (sub-micromolar IC50 values for HDAC1, HDAC2, and HDAC11, ca 2 μM for HDAC3, and >10 μM for HDAC4-8) with broad spectrum antitumor activity in vitro and in vivo. MGCD 0103 induced hyperacetylation of histones, selectively induced apoptosis, caused cell cycle blockade, and exhibited potent and selective antiproliferative activities against a broad spectrum of human cancer cell lines in vitro. KEYWORDS: Mocetinostat | Supplier | HDAC inhibitor | MGCD 0103 | MG 0103 | MG0103 | MGCD0103 | CAS [726169-73-9] | Histone | HDAC1 | HDAC2 | HDAC3 | HDAC11 | deacetylase | antitumor | hyperacetylation | apoptosis | cell cycle | blockade | isotype-selective |
| 產(chǎn)品價(jià)格 | 現(xiàn)貨詢價(jià)，電話：010-67529703 |
| 產(chǎn)品規(guī)格 | |
| 產(chǎn)品品牌 | axonmedchem |
| 產(chǎn)品概述 | |
| 產(chǎn)品詳情 |
Mocetinostat - MGCD 0103 | MG 0103Axon 2505 CAS [726169-73-9] MF C23H20N6O
DescriptionClass I selective HDAC inhibitor (sub-micromolar IC50 values for HDAC1, HDAC2, and HDAC11, ca 2 μM for HDAC3, and >10 μM for HDAC4-8) with broad spectrum antitumor activity in vitro and in vivo. MGCD 0103 induced hyperacetylation of histones, selectively induced apoptosis, caused cell cycle blockade, and exhibited potent and selective antiproliferative activities against a broad spectrum of human cancer cell lines in vitro. KEYWORDS: Mocetinostat | Supplier | HDAC inhibitor | MGCD 0103 | MG 0103 | MG0103 | MGCD0103 | CAS [726169-73-9] | Histone | HDAC1 | HDAC2 | HDAC3 | HDAC11 | deacetylase | antitumor | hyperacetylation | apoptosis | cell cycle | blockade | isotype-selective
Class I selective HDAC inhibitor with broad spectrum antitumor activity
Chemical nameN-(2-aminophenyl)-4-((4-(pyridin-3-yl)pyrimidin-2-ylamino)methyl)benzamide Parent CAS No.[726169-73-9] |
| 產(chǎn)品資料 |
