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產(chǎn)品名稱

CI 994 - PD 123654 | Tacedinaline

產(chǎn)品貨號(hào)

Axon 2014 CAS [112522-64-2] MF C15H15N3O2MW 269.30 Purity: 98% Soluble in DMSO Description Orally bioavailable histone deacetylase (HDAC) inhibitor that causes histone hyperacetylation in living cells. CI-994 inhibited HDAC1 and HDAC2 in a concentration-dependent fashion; mediates G1 cell cycle arrest, inhibits proliferation and induces apoptosis in vitro and in vivo References Certificates Categories Extra info AG Kraker et al. Modulation of histone acetylation by [4-(acetylamino)-N-(2-amino-phenyl) benzamide] in HCT-8 colon carcinoma. Mol. Cancer Ther. 2003, (4), 401-408.? ? M Loprevite et al. In Vitro Study of CI-994, a Histone Deacetylase Inhibitor, in Non-Small Cell Lung Cancer Cell Lines. Oncol. Res. Feat. Preclin. Clin. Cancer Ther. 2005,?15(1), 39-48.? Certificate of Analysis Material Safety Data Sheet Apoptosis Cell Cycle Regulation Cell Signaling & Oncology Epigenetics DNA-damage Response EC 3.5.1.98 HDAC Pfizer Licensed Products HDAC inhibitor that causes histone hyperacetylation in living cells Chemical name 4-acetamido-N-(2-aminophenyl)benzamide Source information Pfizer compound; Sold for research purposes under agreement from Pfizer Inc. Parent CAS No. [112522-64-2] Order Size Unit Price Stock 10 mg €70.00 In Stock

產(chǎn)品價(jià)格

現(xiàn)貨詢價(jià)，電話：010-67529703

產(chǎn)品規(guī)格

產(chǎn)品品牌

axonmedchem

產(chǎn)品概述

產(chǎn)品詳情

CI 994 - PD 123654 | Tacedinaline

Based on 14 reference(s) in Google Scholar 8 10 14

Axon 2014

CAS [112522-64-2]

MF C15H15N3O2
MW 269.30

Purity: 98%
Soluble in DMSO

CI 994

Description

Orally bioavailable histone deacetylase (HDAC) inhibitor that causes histone hyperacetylation in living cells. CI-994 inhibited HDAC1 and HDAC2 in a concentration-dependent fashion; mediates G1 cell cycle arrest, inhibits proliferation and induces apoptosis in vitro and in vivo

AG Kraker et al. Modulation of histone acetylation by [4-(acetylamino)-N-(2-amino-phenyl) benzamide] in HCT-8 colon carcinoma. Mol. Cancer Ther. 2003, (4), 401-408.?

M Loprevite et al. In Vitro Study of CI-994, a Histone Deacetylase Inhibitor, in Non-Small Cell Lung Cancer Cell Lines. Oncol. Res. Feat. Preclin. Clin. Cancer Ther. 2005,?15(1), 39-48.?

Certificate of Analysis
Material Safety Data Sheet

Apoptosis Cell Cycle Regulation Cell Signaling & Oncology Epigenetics DNA-damage Response EC 3.5.1.98 HDAC Pfizer Licensed Products

HDAC inhibitor that causes histone hyperacetylation in living cells

Chemical name

4-acetamido-N-(2-aminophenyl)benzamide

Source information

Pfizer compound; Sold for research purposes under agreement from Pfizer Inc.

Parent CAS No.

[112522-64-2]

產(chǎn)品資料

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