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產(chǎn)品名稱

HDAC6 inhibitor ISOX

產(chǎn)品貨號

Axon 1645 CAS [1045792-66-2] MF C22H30N4O6MW 446.50 Purity: 99% Soluble in DMSO Description Potent and selective histone deacetylase 6 (HDAC6) inhibitor, with IC50 to be 2.4 nM (HDAC6) and 71 nM (HDAC1). (*2010 revised affinities). KEYWORDS: HDAC6 inhibitor ISOX | supplier | HDAC6 inhibitor | ISOX | CAS [1045792-66-2] | Histone | HDAC | Inhibitor | Enzymes

產(chǎn)品價格

現(xiàn)貨詢價，電話：010-67529703

產(chǎn)品規(guī)格

產(chǎn)品品牌

axonmedchem

產(chǎn)品概述

產(chǎn)品詳情

HDAC6 inhibitor ISOX

Based on 14 reference(s) in Google Scholar 8 10 14

Axon 1645

CAS [1045792-66-2]

MF C22H30N4O6
MW 446.50

Purity: 99%
Soluble in DMSO

HDAC6 inhibitor ISOX

Description

Potent and selective histone deacetylase 6 (HDAC6) inhibitor, with IC50 to be 2.4 nM (HDAC6) and 71 nM (HDAC1). (*2010 revised affinities).

KEYWORDS: HDAC6 inhibitor ISOX | supplier | HDAC6 inhibitor | ISOX | CAS [1045792-66-2] | Histone | HDAC | Inhibitor | Enzymes

KV Butler et al. Rational Design and Simple Chemistry Yield a Superior,?Neuroprotective HDAC6 Inhibitor, Tubastatin A. J. Am. Chem. Soc. 2010, 132, 10842–10846.

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AP Kozikowski et al.?Use of the Nitrile Oxide Cycloaddition (NOC) Reaction for Molecular Probe Generation: A New Class of Enzyme Selective Histone Deacetylase Inhibitors (HDACIs) Showing Picomolar Activity at HDAC6. J. Med. Chem. 2008, 51, 4370–4373.

Certificate of Analysis
Material Safety Data Sheet

Apoptosis Cell Cycle Regulation Cell Signaling & Oncology Epigenetics DNA-damage Response EC 3.5.1.98 HDAC

HDAC6 Inhibitor

Chemical name

tert-butyl 4-(3-(7-(hydroxyamino)-7-oxoheptylcarbamoyl)isoxazol-5-yl)phenylcarbamate

Parent CAS No.

[1045792-66-2]

產(chǎn)品資料

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