<button id="eiezk"><video id="eiezk"></video></button>

產(chǎn)品名稱

SU 11274

產(chǎn)品貨號

Axon 1581 CAS [658084-23-2] MF C28H30ClN5O4SMW 568.09 Purity: 99% Soluble in DMSO Description ATP-competitive and selective MET inhibitor; inhibition of the Met kinase activity by SU11274 led to time- and dose-dependent reduced cell growth and induced G1 cell cycle arrest and apoptosis References Certificates Categories Extra info S Berthou et al. The Met kinase inhibitor SU11274 exhibits a selective inhibition pattern toward different receptor mutated variants. Oncogene 2004, 23, 5387-5393.? ? PC Ma et al. Functional expression and mutations of c-Met and its therapeutic inhibition with SU11274 and small interfering RNA in non-small cell lung cancer. Cancer Res. 2005, 65, 1479-1488.? Certificate of Analysis Material Safety Data Sheet Apoptosis Cell Cycle Regulation Cell Signaling & Oncology c-MET RTK class X; EC 2.7.10.1 ATP-competitive inhibitor of c-MET Chemical name (Z)-N-(3-chlorophenyl)-3-((3,5-dimethyl-4-(4-methylpiperazine-1-carbonyl)-1H-pyrrol-2-yl)methylene)-N-methyl-2-oxoindoline-5-sulfonamide Parent CAS No. [658084-23-2] Order Size Unit Price Stock 5 mg €95.00 In Stock

產(chǎn)品價格

現(xiàn)貨詢價，電話：010-67529703

產(chǎn)品規(guī)格

產(chǎn)品品牌

axonmedchem

產(chǎn)品概述

產(chǎn)品詳情

SU 11274

Based on 18 reference(s) in Google Scholar 9 10 18

Axon 1581

CAS [658084-23-2]

MF C28H30ClN5O4S
MW 568.09

Purity: 99%
Soluble in DMSO

SU 11274

Description

ATP-competitive and selective MET inhibitor; inhibition of the Met kinase activity by SU11274 led to time- and dose-dependent reduced cell growth and induced G1 cell cycle arrest and apoptosis

S Berthou et al. The Met kinase inhibitor SU11274 exhibits a selective inhibition pattern toward different receptor mutated variants. Oncogene 2004, 23, 5387-5393.?

PC Ma et al. Functional expression and mutations of c-Met and its therapeutic inhibition with SU11274 and small interfering RNA in non-small cell lung cancer. Cancer Res. 2005, 65, 1479-1488.?

Certificate of Analysis
Material Safety Data Sheet

Apoptosis Cell Cycle Regulation Cell Signaling & Oncology c-MET RTK class X; EC 2.7.10.1

ATP-competitive inhibitor of c-MET

Chemical name

(Z)-N-(3-chlorophenyl)-3-((3,5-dimethyl-4-(4-methylpiperazine-1-carbonyl)-1H-pyrrol-2-yl)methylene)-N-methyl-2-oxoindoline-5-sulfonamide

Parent CAS No.

[658084-23-2]

產(chǎn)品資料

<button id="eiezk"><video id="eiezk"></video></button>