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產(chǎn)品名稱

UK 356618 - PF 03890101

產(chǎn)品貨號(hào)

Axon 2111 CAS [230961-08-7] MF C34H43N3O4MW 557.72 Purity: 98% Optical purity: Optically pure Soluble in DMSO Description Potent and selective matrix metalloprotease-3 (MMP-3 aka stromelysin-1) inhibitor (IC50=5.9 nM); >140-fold selective over MMP-1, MMP-2, MMP-9 and MMP-14 References Certificates Categories Extra info MJ Fray et al. Discovery of potent and selective succinyl hydroxamate inhibitors of matrix metalloprotease-3 (Stromelysin-1). Bioorg. Med. Chem. Lett. 2001, 11(4), 571-574.? ? MJ Fray et al. A potent, selective inhibitor of matrix metalloproteinase-3 for the topical treatment of chronic dermal ulcers. J. Med Chem. 2003, 46(16), 3514-3525.? Certificate of Analysis Material Safety Data Sheet Angiogenesis Cell Signaling & Oncology Miscellaneous Pain & Inflammation EC 3.4.24.17 MMP Pfizer Licensed Products Potent MMP-3 (aka Stromelysin-1) inhibitor Chemical name (R)-N1-((S)-3,3-dimethyl-1-oxo-1-((R)-1-phenylethylamino)butan-2-yl)-N4-hydroxy-2-(3-(2-methylbiphenyl-4-yl)propyl)succinamide Source information Pfizer compound; Sold for research purposes under agreement from Pfizer Inc. Parent CAS No. [230961-08-7] Order Size Unit Price Stock 5 mg €90.00 In Stock

產(chǎn)品價(jià)格

現(xiàn)貨詢價(jià)，電話：010-67529703

產(chǎn)品規(guī)格

產(chǎn)品品牌

axonmedchem

產(chǎn)品概述

產(chǎn)品詳情

UK 356618 - PF 03890101

Based on 15 reference(s) in Google Scholar 8 10 15

Axon 2111

CAS [230961-08-7]

MF C34H43N3O4
MW 557.72

Purity: 98%
Optical purity: Optically pure
Soluble in DMSO

UK 356618

Description

Potent and selective matrix metalloprotease-3 (MMP-3 aka stromelysin-1) inhibitor (IC50=5.9 nM); >140-fold selective over MMP-1, MMP-2, MMP-9 and MMP-14

MJ Fray et al. Discovery of potent and selective succinyl hydroxamate inhibitors of matrix metalloprotease-3 (Stromelysin-1). Bioorg. Med. Chem. Lett. 2001, 11(4), 571-574.?

MJ Fray et al. A potent, selective inhibitor of matrix metalloproteinase-3 for the topical treatment of chronic dermal ulcers. J. Med Chem. 2003, 46(16), 3514-3525.?

Certificate of Analysis
Material Safety Data Sheet

Angiogenesis Cell Signaling & Oncology Miscellaneous Pain & Inflammation EC 3.4.24.17 MMP Pfizer Licensed Products

Potent MMP-3 (aka Stromelysin-1) inhibitor

Chemical name

(R)-N1-((S)-3,3-dimethyl-1-oxo-1-((R)-1-phenylethylamino)butan-2-yl)-N4-hydroxy-2-(3-(2-methylbiphenyl-4-yl)propyl)succinamide

Source information

Pfizer compound; Sold for research purposes under agreement from Pfizer Inc.

Parent CAS No.

[230961-08-7]

產(chǎn)品資料

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