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產(chǎn)品名稱

Foretinib - GSK 1363089 | Exel 2880 | XL 880

產(chǎn)品貨號(hào)

Axon 1582 CAS [849217-64-7] MF C34H34F2N4O6MW 632.65 Purity: 98% Soluble in DMSO Description An orally available inhibitor targeting c-MET (IC50: 0.4 nM) and VEGFR2 References Certificates Categories Extra info JP Eder et al. A Phase I Dose-Escalation Study to Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Early Antitumor Activity of Foretinib. Clin. Cancer Res. 2010, 16(13),?3507. ? L Liu?et al. Novel mechanism of lapatinib resistance in HER2-positive breast tumor cells: activation of AXL. Cancer Res. 2009, 69(17), 6871-8.? Certificate of Analysis Material Safety Data Sheet Cell Signaling & Oncology c-MET RTK class X; EC 2.7.10.1 c-MET and VEGFR2 tyrosine kinase inhibitor Chemical name N-(4-(7-(3-morpholinopropoxy)-6-methoxyquinolin-4-yloxy)-3-fluorophenyl)-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide Parent CAS No. [849217-64-7] Order Size Unit Price Stock 5 mg €90.00 In Stock

產(chǎn)品價(jià)格

現(xiàn)貨詢價(jià)，電話：010-67529703

產(chǎn)品規(guī)格

產(chǎn)品品牌

axonmedchem

產(chǎn)品概述

產(chǎn)品詳情

Foretinib - GSK 1363089 | Exel 2880 | XL 880

Based on 12 reference(s) in Google Scholar 9 10 12

Axon 1582

CAS [849217-64-7]

MF C34H34F2N4O6
MW 632.65

Purity: 98%
Soluble in DMSO

Foretinib

Description

An orally available inhibitor targeting c-MET (IC50: 0.4 nM) and VEGFR2

JP Eder et al. A Phase I Dose-Escalation Study to Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Early Antitumor Activity of Foretinib. Clin. Cancer Res. 2010, 16(13),?3507.

L Liu?et al. Novel mechanism of lapatinib resistance in HER2-positive breast tumor cells: activation of AXL. Cancer Res. 2009, 69(17), 6871-8.?

Certificate of Analysis
Material Safety Data Sheet

Cell Signaling & Oncology c-MET RTK class X; EC 2.7.10.1

c-MET and VEGFR2 tyrosine kinase inhibitor

Chemical name

N-(4-(7-(3-morpholinopropoxy)-6-methoxyquinolin-4-yloxy)-3-fluorophenyl)-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide

Parent CAS No.

[849217-64-7]

產(chǎn)品資料

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