| 產(chǎn)品名稱 | ZB716 |
| 產(chǎn)品貨號 | Axon 2652 CAS [1853279-29-4] MF C32H48BF5O4SMW 634.59 Purity: 99% Optical purity: Optically pure Soluble in DMSO Description ZB716 is a steroidal, orally bioavailable SERD (selective estrogen receptor downregulator) that binds to ER with high affinity and exerts its antiestrogenic effect on ER-expressing breast cancer cells. In both tamoxifen-naive and tamoxifen-resistant breast cancer cells, ZB716 potently inhibits cell proliferation and effectively degrades the hormone receptor in a dose-dependent manner. ZB716 is shown to have far superior oral bioavailability in mice when compared to fulvestrant. * Sold in collaboration with Zenopharm, LLC |
| 產(chǎn)品價格 | 現(xiàn)貨詢價，電話：010-67529703 |
| 產(chǎn)品規(guī)格 | |
| 產(chǎn)品品牌 | axonmedchem |
| 產(chǎn)品概述 | |
| 產(chǎn)品詳情 |
ZB716Axon 2652 CAS [1853279-29-4] MF C32H48BF5O4S
DescriptionZB716 is a steroidal, orally bioavailable SERD (selective estrogen receptor downregulator) that binds to ER with high affinity and exerts its antiestrogenic effect on ER-expressing breast cancer cells. In both tamoxifen-naive and tamoxifen-resistant breast cancer cells, ZB716 potently inhibits cell proliferation and effectively degrades the hormone receptor in a dose-dependent manner. ZB716 is shown to have far superior oral bioavailability in mice when compared to fulvestrant. * Sold in collaboration with Zenopharm, LLC KEYWORDS: ZB716 | supplier | SERD | ZB-716 | CAS [1853279-29-4] | Estrogen | Estrogen (ER) | Downregulator | selective estrogen receptor downregulator | nuclear | steroidal | breast cancer | cell proliferation
Steroidal, orally bioavailable SERD
Chemical name(7R,8R,9S,13S,14S,17S)-17-hydroxy-13-methyl-7-(9-(4,4,5,5,5-pentafluoropentylsulfinyl)nonyl)-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-3-ylboronic acid Source informationSold in collaboration with Zenopharm, LLCParent CAS No.[1853279-29-4] |
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