| 產(chǎn)品名稱 | ITD 1 |
| 產(chǎn)品貨號(hào) | Axon 2323 CAS [1099644-42-4] MF C27H29NO3MW 415.52 Purity: 98% Soluble in DMSO Description Selective inhibitor of TGFβ/Smad signaling (IC50 value 0.85 μM; 83% TGF-β inhibiton at 2.5 μM) that acts by clearing the type II TGFβ receptor from the cell surface. ITD1 stimulates the differentiation of cardiomyocytes and promote cardiogenesis in murine embryonic stem cell (mESCs). TGFβ inhibition by the (+)-eneatiomer is approximately 15-fold more effective than by its (?)-enantiomer. Note |
| 產(chǎn)品價(jià)格 | 現(xiàn)貨詢價(jià),電話:010-67529703 |
| 產(chǎn)品規(guī)格 | |
| 產(chǎn)品品牌 | axonmedchem |
| 產(chǎn)品概述 | |
| 產(chǎn)品詳情 |
ITD 1Axon 2323 CAS [1099644-42-4] MF C27H29NO3
DescriptionSelective inhibitor of TGFβ/Smad signaling (IC50 value 0.85 μM; 83% TGF-β inhibiton at 2.5 μM) that acts by clearing the type II TGFβ receptor from the cell surface. ITD1 stimulates the differentiation of cardiomyocytes and promote cardiogenesis in murine embryonic stem cell (mESCs). TGFβ inhibition by the (+)-eneatiomer is approximately 15-fold more effective than by its (?)-enantiomer. Note: The optically pure (+)-ITD 1 (Axon 2467) is available as well KEYWORDS: ITD 1 | supplier | TGF-βR2 inhibitor | ITD1 | CAS [1099644-42-4] | TGF-β | TGF-βR | Antagonist | Smad | type II | differentiation | cardiomyocytes | cardiogenesis | embryonic stem cell | mESCs
Selective inhibitor of TGFβ/Smad signaling that promotes cardiogenesis
Chemical nameethyl 4-(biphenyl-4-yl)-2,7,7-trimethyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate Parent CAS No.[1099644-42-4] |
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