| 產(chǎn)品名稱(chēng) | FH535 sodium salt |
| 產(chǎn)品貨號(hào) | Axon 2706 CAS [N.A.] MF C13H9Cl2N2NaO4SMW 383.18 Purity: 99% Soluble in water and DMSO Description Small-molecule dual inhibitor of peroxisome proliferator-activated receptor (PPAR) and Wnt/β-catenin/TCF/LEF signaling. FH535 inhibits recruitment of the coactivators β-catenin and GRIP1, but not the corepressors NCoR and SMRT. FH535 is selectively toxic to carcinomas expressing the Wnt/β-Catenin pathway, and known to inhibit invasion, migration, and growth in vitro in multiple types of cancer, such as liver cancer and triple negative breast cancer cell lines; water soluble sodium salt form of FH535 (Axon 2686). KEYWORDS: FH535 sodium salt | supplier | Dual Wnt/β-catenin and PPAR inhibitor | FH-535 sodium salt | FH 535 sodium salt | CAS [108409-83-2] | Metabolism | PPARγ | PPARδ | peroxisome proliferator–activated receptor | Nuclear | NR1C | Tcf/Lef |
| 產(chǎn)品價(jià)格 | 現(xiàn)貨詢(xún)價(jià)，電話(huà)：010-67529703 |
| 產(chǎn)品規(guī)格 | |
| 產(chǎn)品品牌 | axonmedchem |
| 產(chǎn)品概述 | |
| 產(chǎn)品詳情 |
FH535 sodium saltAxon 2706 CAS [N.A.] MF C13H9Cl2N2NaO4S
DescriptionSmall-molecule dual inhibitor of peroxisome proliferator-activated receptor (PPAR) and Wnt/β-catenin/TCF/LEF signaling. FH535 inhibits recruitment of the coactivators β-catenin and GRIP1, but not the corepressors NCoR and SMRT. FH535 is selectively toxic to carcinomas expressing the Wnt/β-Catenin pathway, and known to inhibit invasion, migration, and growth in vitro in multiple types of cancer, such as liver cancer and triple negative breast cancer cell lines; water soluble sodium salt form of FH535 (Axon 2686). KEYWORDS: FH535 sodium salt | supplier | Dual Wnt/β-catenin and PPAR inhibitor | FH-535 sodium salt | FH 535 sodium salt | CAS [108409-83-2] | Metabolism | PPARγ | PPARδ | peroxisome proliferator–activated receptor | Nuclear | NR1C | Tcf/Lef
Dual inhibitor of PPAR and Wnt/β-catenin signaling
Chemical nameSodium (2,5-dichlorophenylsulfonyl)(2-methyl-4-nitrophenyl)amide Parent CAS No.[108409-83-2] |
| 產(chǎn)品資料 |
