| 產(chǎn)品名稱 | ML346 - CID 767276 |
| 產(chǎn)品貨號(hào) | Axon 2703 CAS [100872-83-1] MF C14H12N2O4MW 272.26 Purity: 100% Soluble in DMSO Description ML346 is an activator of Hsp70 (EC50 value of 4.6 μM; HeLa cell toxicity assay). ML346 induces HSF-1-dependent chaperone expression and restores protein folding in conformational disease models. These effects are mediated by novel mechanisms involving FOXO, HSF-1, and Nfr-2. ML346 has good chemical stability, is not reactive with excess glutathione, and is cell permeable. KEYWORDS: ML346 | supplier | Hsp70 activator | CID 767276 | ML 346 | ML-346 | CID767276 | CID-767276 | CAS [100872-83-1] | CAS [1423118-63-1] | Unfolded Protein Response (Non Selective) | Hsp70 | Activator | Enzymes | ARE | Heat Shock Response | HSR | Probe | Proteostasis | HSF-1 |
| 產(chǎn)品價(jià)格 | 現(xiàn)貨詢價(jià)，電話：010-67529703 |
| 產(chǎn)品規(guī)格 | |
| 產(chǎn)品品牌 | axonmedchem |
| 產(chǎn)品概述 | |
| 產(chǎn)品詳情 |
ML346 - CID 767276Axon 2703 CAS [100872-83-1] MF C14H12N2O4
DescriptionML346 is an activator of Hsp70 (EC50 value of 4.6 μM; HeLa cell toxicity assay). ML346 induces HSF-1-dependent chaperone expression and restores protein folding in conformational disease models. These effects are mediated by novel mechanisms involving FOXO, HSF-1, and Nfr-2. ML346 has good chemical stability, is not reactive with excess glutathione, and is cell permeable. KEYWORDS: ML346 | supplier | Hsp70 activator | CID 767276 | ML 346 | ML-346 | CID767276 | CID-767276 | CAS [100872-83-1] | CAS [1423118-63-1] | Unfolded Protein Response (Non Selective) | Hsp70 | Activator | Enzymes | ARE | Heat Shock Response | HSR | Probe | Proteostasis | HSF-1
Hsp70 activator
Chemical name5-(3-(4-Methoxyphenyl)allylidene)pyrimidine-2,4,6(1H,3H,5H)-trione Parent CAS No.[100872-83-1] |
| 產(chǎn)品資料 |
