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產(chǎn)品名稱

STA 9090 - Ganetespib

產(chǎn)品貨號

產(chǎn)品價格

現(xiàn)貨詢價，電話：010-67529703

產(chǎn)品規(guī)格

產(chǎn)品品牌

axonmedchem

產(chǎn)品概述

產(chǎn)品詳情

STA 9090 - Ganetespib

Based on 14 reference(s) in Google Scholar 8 10 14

Axon 1968

CAS [888216-25-9]

MF C20H20N4O3
MW 364.40

Purity: 99%
Soluble in 0.1N NaOH(aq) and DMSO

STA 9090

Description

Hsp90 inhibitor; exhibits potent antitumor activity and a superior safety profile for cancer therapy; with potent in vitro and in vivo activity in tumor cells harboring constitutively active JAK/STAT signaling.

J Acquaviva et al. Targeting KRAS-Mutant Nona€“Small Cell Lung Cancer with the Hsp90 Inhibitor Ganetespib. Mol. Cancer Ther. 2012, 11, 2633-2643.?

W Ying et al. Ganetespib, a unique triazolone-containing Hsp90 inhibitor, exhibits potent antitumor activity and a superior safety profile for cancer therapy. Mol Cancer Ther. 2012, 11(2), 475-484.?

DA Proia et al. Multifaceted Intervention by the Hsp90 Inhibitor Ganetespib (STA-9090) in Cancer Cells with Activated JAK/STAT Signaling.?PLoS ONE 2011, 6(4), e18552.?

T Shimamura et al. Ganetespib (STA-9090), a Nongeldanamycin HSP90 Inhibitor, Has Potent Antitumor Activity in In Vitro and In Vivo Models of Nona€“Small Cell Lung Cancer. Clin. Cancer Res. 2012, 18, 4973.?

Certificate of Analysis
Material Safety Data Sheet

Apoptosis Cardiovascular Cell Cycle Regulation Cell Signaling & Oncology Hsp90 EC 3.6

Hsp90 inhibitor

Chemical name

3-(2,4-dihydroxy-5-isopropylphenyl)-4-(1-methyl-1H-indol-5-yl)-1H-1,2,4-triazol-5(4H)-one

Parent CAS No.

[888216-25-9]

產(chǎn)品資料

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