| 產(chǎn)品名稱 | TFB-TBOA |
| 產(chǎn)品貨號 | Axon 2640 CAS [480439-73-4] MF C19H17F3N2O6MW 426.34 Purity: 100% Optical purity: >97% d.e. Soluble in 0.1N NaOH(aq) and DMSO Description Very potent blocker for the human excitatory amino acid transporters (IC50 values 22 nM, 17 nM, and 300 nM, for EAAT1, EAAT2, and EAAT3, respectively). TFB-BOA is more potent at inhibiting EAAT1 and EAAT2 compared with L-TBOA (Axon 2427), and induced spontaneous epileptiform discharges and convulsive behaviors in mice. An important tool for elucidation of the physiological roles of EAATs and their contribution to the etiology of neuronal disorders. KEYWORDS: TFB-TBOA | supplier | EAAT blocker | L-TFB-TBOA | CAS [480439-73-4] | Glutamate | EAAT1 | EAAT2 | Blocker | excitatory amino acid transporter | convulsion | neuronal | CNS |
| 產(chǎn)品價格 | 現(xiàn)貨詢價，電話：010-67529703 |
| 產(chǎn)品規(guī)格 | |
| 產(chǎn)品品牌 | axonmedchem |
| 產(chǎn)品概述 | |
| 產(chǎn)品詳情 |
TFB-TBOAAxon 2640 CAS [480439-73-4] MF C19H17F3N2O6
DescriptionVery potent blocker for the human excitatory amino acid transporters (IC50 values 22 nM, 17 nM, and 300 nM, for EAAT1, EAAT2, and EAAT3, respectively). TFB-BOA is more potent at inhibiting EAAT1 and EAAT2 compared with L-TBOA (Axon 2427), and induced spontaneous epileptiform discharges and convulsive behaviors in mice. An important tool for elucidation of the physiological roles of EAATs and their contribution to the etiology of neuronal disorders. KEYWORDS: TFB-TBOA | supplier | EAAT blocker | L-TFB-TBOA | CAS [480439-73-4] | Glutamate | EAAT1 | EAAT2 | Blocker | excitatory amino acid transporter | convulsion | neuronal | CNS
Very potent blocker of human excitatory amino acid transporters (EAAT1-2)
Chemical name(2S,3S)-2-amino-3-(3-(4-(trifluoromethyl)benzamido)benzyloxy)succinic acid Parent CAS No.[480439-73-4] |
| 產(chǎn)品資料 |
