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產(chǎn)品名稱

VU 0364439

產(chǎn)品貨號

Axon 1830 CAS [1246086-78-1] MF C18H13Cl2N3O3SMW 422.29 Purity: 99% Soluble in DMSO Description Very potent positive allosteric modulator (PAM) of metabotropic glutamate receptor subtype 4 (mGluR4) (EC50: 19.8 nM) References Certificates Categories Extra info DW Engers et al. Synthesis and SAR of novel, 4-(phenylsulfamoyl)phenylacetamide mGlu4 positive allosteric modulators (PAMs) identified by functional high-throughput screening (HTS).?Bioorg. Med. Chem. Lett. 2010, 20(17), 5175-5178.? ? AJ Robichaud et al. Recent Progress on the Identification of Metabotropic Glutamate 4 Receptor Ligands and Their Potential Utility as CNS Therapeutics. ACS Chem. Neurosci. 2011, 2(8), 433–449.? Certificate of Analysis Material Safety Data Sheet CNS Pain & Inflammation mGluR4 C3 Positive allosteric modulator (PAM) of mGluR4 Chemical name N-(3-chloro-4-(N-(2-chlorophenyl)sulfamoyl)phenyl)picolinamide Parent CAS No. [1246086-78-1] Order Size Unit Price Stock 10 mg €115.00 In Stock

產(chǎn)品價格

現(xiàn)貨詢價，電話：010-67529703

產(chǎn)品規(guī)格

產(chǎn)品品牌

axonmedchem

產(chǎn)品概述

產(chǎn)品詳情

VU 0364439

Based on 16 reference(s) in Google Scholar 9 10 16

Axon 1830

CAS [1246086-78-1]

MF C18H13Cl2N3O3S
MW 422.29

Purity: 99%
Soluble in DMSO

VU 0364439

Description

Very potent positive allosteric modulator (PAM) of metabotropic glutamate receptor subtype 4 (mGluR4) (EC50: 19.8 nM)

DW Engers et al. Synthesis and SAR of novel, 4-(phenylsulfamoyl)phenylacetamide mGlu4 positive allosteric modulators (PAMs) identified by functional high-throughput screening (HTS).?Bioorg. Med. Chem. Lett. 2010, 20(17), 5175-5178.?

AJ Robichaud et al. Recent Progress on the Identification of Metabotropic Glutamate 4 Receptor Ligands and Their Potential Utility as CNS Therapeutics. ACS Chem. Neurosci. 2011, 2(8), 433–449.?

Certificate of Analysis
Material Safety Data Sheet

CNS Pain & Inflammation mGluR4 C3

Positive allosteric modulator (PAM) of mGluR4

Chemical name

N-(3-chloro-4-(N-(2-chlorophenyl)sulfamoyl)phenyl)picolinamide

Parent CAS No.

[1246086-78-1]

產(chǎn)品資料

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