| 產(chǎn)品名稱 | S 18986 |
| 產(chǎn)品貨號(hào) | Axon 1788 CAS [175340-20-2] MF C10H12N2O2SMW 224.28 Purity: 99% Optical purity: >99% ee Soluble in DMSO Description Positive allosteric modulator of AMPA receptor with cognitive-enhancing effects; neuroprotective; long-acting and with good oral availability References Certificates Categories Extra info B?Lockhart?et al.?(S)-2,3-dihydro-[3,4]cyclopentano-1,2,4-benzothiadiazine-1,1-dioxide: (S18986-1) a positive modulator of AMPA receptors enhances (S)-AMPA-mediated [3H]noradrenaline release (...). Eur. J. Pharmacol. 2000, 401(2), 145–153. ? C Lebrun?et al.?Effects of S 18986-1, a novel cognitive enhancer, on memory performances in an object recognition task in rats. Eur. J. Pharmacol. 2000, 401(2), 205–212. ? SM Gupta?et al.?GAP-43 is essential for the neurotrophic effects of BDNF and positive AMPA receptor modulator S18986. Cell Death Differ. 2009, 16(4), 624–637.?? ? KD?Destot-Wong?et al.?The AMPA receptor positive allosteric modulator, S18986, is neuroprotective against neonatal excitotoxic and inflammatory brain damage through BDNF synthesis. Neuropharmacology 2009, 57(3), 277–286. Certificate of Analysis Material Safety Data Sheet CNS Pain & Inflammation AMPA Unclassified Positive allosteric modulator of AMPA receptor Chemical name (+)-(S)-2,3,3a,4-Tetrahydro-1H-pyrrolo[2,1-c][1,2,4]benzothiadiazine-5,5-dioxide Parent CAS No. [175340-20-2] Order Size Unit Price Stock 5 mg €105.00 In Stock |
| 產(chǎn)品價(jià)格 | 現(xiàn)貨詢價(jià)，電話：010-67529703 |
| 產(chǎn)品規(guī)格 | |
| 產(chǎn)品品牌 | axonmedchem |
| 產(chǎn)品概述 | |
| 產(chǎn)品詳情 |
S 18986Axon 1788 CAS [175340-20-2] MF C10H12N2O2S
Description
Positive allosteric modulator of AMPA receptor with cognitive-enhancing effects; neuroprotective; long-acting and with good oral availability
Positive allosteric modulator of AMPA receptor
Chemical name(+)-(S)-2,3,3a,4-Tetrahydro-1H-pyrrolo[2,1-c][1,2,4]benzothiadiazine-5,5-dioxide Parent CAS No.[175340-20-2] |
| 產(chǎn)品資料 |
