| 產(chǎn)品名稱 | iCRT5 - CRT Inhibitor iCRT5 |
| 產(chǎn)品貨號(hào) | Axon 2133 CAS [18623-44-4] MF C16H17NO5S2MW 367.44 Purity: 99% Soluble in DMSO Description Potent and cell-permeable β-catenin-responsive transcription (CRT) inhibitor, with IC50 value of 18 nM for Wnt responsive STF16 luciferase (STF16-Luc). iCRT5 acts by disrupting the interaction between β-catenin and TCF4, possibly by direct binding to β-catenin, while displaying minimal or less prominent effect on non-canonical Wnt signaling and other pathways such as Hh, JAK/STAT, and Notch signaling References Certificates Categories Extra info Certificate of Analysis Material Safety Data Sheet Cell Signaling & Oncology Stem Cell β-Catenin Wnt-β-Catenin Cell-Cell Adhesion Protein Wnt β-Catenin-responsive transcription (CRT) inhibitor Chemical name 4-(5-(3,4-dimethoxybenzylidene)-4-oxo-2-thioxothiazolidin-3-yl)butanoic acid Parent CAS No. [18623-44-4] Order Size Unit Price Stock 10 mg €80.00 In Stock |
| 產(chǎn)品價(jià)格 | 現(xiàn)貨詢價(jià)，電話：010-67529703 |
| 產(chǎn)品規(guī)格 | |
| 產(chǎn)品品牌 | axonmedchem |
| 產(chǎn)品概述 | |
| 產(chǎn)品詳情 |
iCRT5 - CRT Inhibitor iCRT5Axon 2133 CAS [18623-44-4] MF C16H17NO5S2
Description
Potent and cell-permeable β-catenin-responsive transcription (CRT) inhibitor, with IC50 value of 18 nM for Wnt responsive STF16 luciferase (STF16-Luc). iCRT5 acts by disrupting the interaction between β-catenin and TCF4, possibly by direct binding to β-catenin, while displaying minimal or less prominent effect on non-canonical Wnt signaling and other pathways such as Hh, JAK/STAT, and Notch signaling
β-Catenin-responsive transcription (CRT) inhibitor
Chemical name4-(5-(3,4-dimethoxybenzylidene)-4-oxo-2-thioxothiazolidin-3-yl)butanoic acid Parent CAS No.[18623-44-4] |
| 產(chǎn)品資料 |
