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產(chǎn)品名稱(chēng)

PNU 100480 - PF 02341272 | U 100480 | Sutezolid

產(chǎn)品貨號(hào)

Axon 1762 CAS [168828-58-8] MF C16H20FN3O3SMW 353.41 Purity: 99% Soluble in DMSO Description Antituberculosis (anti-TB) agent under clinical development; potent inhibitor of bacterial protein biosynthesis by interfering with the binding of initiator fMet-tRNA(i)(Met) to the ribosomal peptidyltransferase P-site References Certificates Categories Extra info KN Williams et al. Promising Antituberculosis Activity of the Oxazolidinone PNU-100480 Relative to That of Linezolid in a Murine Model. Antimicrob Agents Chemother. 2009, 53(4), 1314–1319. ? KN Williams et al. Addition of PNU-100480 to first-line drugs shortens the time needed to cure murine tuberculosis. Am. J. Respir. Crit. Care Med. 2009, 180(4), 371-6. ? U Patel et al. Oxazolidinones mechanism of action: inhibition of the first peptide bond formation. J. Biol. Chem. 2001, 276(40), 37199-205. ? CE Barry and JS Blanchard. The Chemical Biology of New Drugs in Development for Tuberculosis. Curr. Opin. Chem. Biol. 2010, 14(4), 456–466. Certificate of Analysis Material Safety Data Sheet Immunology EC 2.3.2.12 Peptidyl Transferase Pfizer Licensed Products Ribosomal peptidyl transferase center (PTC) inhibitor Chemical name (S)-N-((3-(3-fluoro-4-thiomorpholinophenyl)-2-oxooxazolidin-5-yl)methyl)acetamide Source information Pfizer compound; Sold for research purposes under agreement from Pfizer Inc. Parent CAS No. [168828-58-8] Order Size Unit Price Stock 5 mg €80.00 In Stock

產(chǎn)品價(jià)格

現(xiàn)貨詢(xún)價(jià)，電話(huà)：010-67529703

產(chǎn)品規(guī)格

產(chǎn)品品牌

axonmedchem

產(chǎn)品概述

產(chǎn)品詳情

PNU 100480 - PF 02341272 | U 100480 | Sutezolid

Based on 8 reference(s) in Google Scholar 9 10 8

Axon 1762

CAS [168828-58-8]

MF C16H20FN3O3S
MW 353.41

Purity: 99%
Soluble in DMSO

PNU 100480

Description

Antituberculosis (anti-TB) agent under clinical development; potent inhibitor of bacterial protein biosynthesis by interfering with the binding of initiator fMet-tRNA(i)(Met) to the ribosomal peptidyltransferase P-site

KN Williams et al. Promising Antituberculosis Activity of the Oxazolidinone PNU-100480 Relative to That of Linezolid in a Murine Model. Antimicrob Agents Chemother. 2009, 53(4), 1314–1319.

KN Williams et al. Addition of PNU-100480 to first-line drugs shortens the time needed to cure murine tuberculosis. Am. J. Respir. Crit. Care Med. 2009, 180(4), 371-6.

U Patel et al. Oxazolidinones mechanism of action: inhibition of the first peptide bond formation. J. Biol. Chem. 2001, 276(40), 37199-205.

CE Barry and JS Blanchard. The Chemical Biology of New Drugs in Development for Tuberculosis. Curr. Opin. Chem. Biol. 2010, 14(4), 456–466.

Certificate of Analysis
Material Safety Data Sheet

Immunology EC 2.3.2.12 Peptidyl Transferase Pfizer Licensed Products

Ribosomal peptidyl transferase center (PTC) inhibitor

Chemical name

(S)-N-((3-(3-fluoro-4-thiomorpholinophenyl)-2-oxooxazolidin-5-yl)methyl)acetamide

Source information

Pfizer compound; Sold for research purposes under agreement from Pfizer Inc.

Parent CAS No.

[168828-58-8]

產(chǎn)品資料

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