| 產(chǎn)品名稱(chēng) | SCH 727965 - Dinaciclib |
| 產(chǎn)品貨號(hào) | Axon 1776 CAS [779353-01-4] MF C21H28N6O2MW 396.49 Purity: 99% Optical purity: Optically pure Soluble in 0.1N HCl(aq) and DMSO Description Potent and selective cyclin-dependent kinase (CDK) inhibitor, selectively inhibiting CDK1, CDK2, CDK5 and CDK9 with IC50 values of 3, 1, 1 and 4 nM respectively; a potential antineoplastic agent References Certificates Categories Extra info LS Chen et al. Pim kinase inhibitor, SGI-1776, induces apoptosis in CLL lymphocytes. Blood, 2009, 114 (19), 4150-4157. ? SM Mumenthaler et al. Pharmacologic inhibition of Pim kinases alters prostate cancer cell growth and resensitizes chemoresistant cells to taxanes. Mol. Cancer Ther. 2009, 8(10), 2882-2893. Certificate of Analysis Material Safety Data Sheet Cell Cycle Regulation Cell Signaling & Oncology p53-Tumor Suppression EC 2.7.11.22 CDK CDK inhibitor (1, 2, 5, and 9 specific) Chemical name (S)-3-((3-ethyl-5-(2-(2-hydroxyethyl)piperidin-1-yl)pyrazolo[1,5-a]pyrimidin-7-ylamino)methyl)pyridine 1-oxide Parent CAS No. [779353-01-4] Order Size Unit Price Stock 5 mg €105.00 In Stock |
| 產(chǎn)品價(jià)格 | 現(xiàn)貨詢(xún)價(jià)，電話(huà)：010-67529703 |
| 產(chǎn)品規(guī)格 | |
| 產(chǎn)品品牌 | axonmedchem |
| 產(chǎn)品概述 | |
| 產(chǎn)品詳情 |
SCH 727965 - DinaciclibAxon 1776 CAS [779353-01-4] MF C21H28N6O2
Description
Potent and selective cyclin-dependent kinase (CDK) inhibitor, selectively inhibiting CDK1, CDK2, CDK5 and CDK9 with IC50 values of 3, 1, 1 and 4 nM respectively; a potential antineoplastic agent
CDK inhibitor (1, 2, 5, and 9 specific)
Chemical name(S)-3-((3-ethyl-5-(2-(2-hydroxyethyl)piperidin-1-yl)pyrazolo[1,5-a]pyrimidin-7-ylamino)methyl)pyridine 1-oxide Parent CAS No.[779353-01-4] |
| 產(chǎn)品資料 |
