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產(chǎn)品名稱

SNS 314 mesylate

產(chǎn)品貨號

Axon 2906 CAS [1146618-41-8] MF C18H15ClN6OS2.CH4O3SMW 527.04 Purity: 99% Soluble in DMSO Description SNS 314 mesylate is a potent and selective Aurora kinase inhibitor with IC50 values of 9 nM, 31 nM and 3 nM for Aurora A, Aurora B and Aurora C, respectively. Moreover, SNS 314 mesylate displays significant activity in pre-clinical in vivo models. KEYWORDS: SNS 314 mesylate | supplier | Aurora inhibitor | SNS314 mesylate | SNS-314 mesylate | CAS [1146618-41-8] | [1057249-41-8] | Non Selective (Histone; Survivin; Topo; TPX2) | Aurora | Inhibitor | Enzymes

產(chǎn)品價格

現(xiàn)貨詢價，電話：010-67529703

產(chǎn)品規(guī)格

產(chǎn)品品牌

axonmedchem

產(chǎn)品概述

產(chǎn)品詳情

SNS 314 mesylate

Based on 22 reference(s) in Google Scholar 8 10 22

Axon 2906

CAS [1146618-41-8]

MF C18H15ClN6OS2.CH4O3S
MW 527.04

Purity: 99%
Soluble in DMSO

SNS 314 mesylate

Description

SNS 314 mesylate is a potent and selective Aurora kinase inhibitor with IC50 values of 9 nM, 31 nM and 3 nM for Aurora A, Aurora B and Aurora C, respectively. Moreover, SNS 314 mesylate displays significant activity in pre-clinical in vivo models.

JD Oslob et al. Discovery of a potent and selective aurora kinase inhibitor. Bioorg Med Chem Lett. 2008 Sep 1;18(17):4880-4.

Certificate of Analysis
Material Safety Data Sheet

Cell Cycle Regulation Cell Signaling & Oncology Epigenetics EC 2.7.11.1 Aurora

Potent and selective Aurora inhibitor (non-specific)

Chemical name

1-(3-Chlorophenyl)-3-(5-(2-(thieno[3,2-d]pyrimidin-4-ylamino)ethyl)thiazol-2-yl)urea methanesulfonate

Parent CAS No.

[1057249-41-8]

產(chǎn)品資料

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