| 產(chǎn)品名稱 | FG-2216 - YM 311 |
| 產(chǎn)品貨號(hào) | Axon 2570 CAS [223387-75-5] MF C12H9ClN2O4MW 280.66 Purity: 99% Soluble in 0.1N HCl(aq) and DMSO Description Orally active HIF prolyl 4-hydroxylase inhibitor (P4-HI; IC50 value 3.9 μM for PHD2) that increases plasma EPO levels up to 30-fold in hemodialysis (HD) patients, and reduces cardiac remodeling after myocardial infarction in rats independent of a reduction of collagen maturation or altering growth factors. KEYWORDS: FG-2216 | supplier | PHD inhibitor | YM 311 | FG2216 | YM311 | CAS [223387-75-5] | Hypoxia-signaling cascade | PHD-2 (HIF1) | PHD-4 (HIF1) | Inhibitor | hypoxia inducible factor | prolyl hydroxylase | EPO | hemodialysis | cardiac remodeling | myocardial infarction | collagen |
| 產(chǎn)品價(jià)格 | 現(xiàn)貨詢價(jià)，電話：010-67529703 |
| 產(chǎn)品規(guī)格 | |
| 產(chǎn)品品牌 | axonmedchem |
| 產(chǎn)品概述 | |
| 產(chǎn)品詳情 |
FG-2216 - YM 311Axon 2570 CAS [223387-75-5] MF C12H9ClN2O4
DescriptionOrally active HIF prolyl 4-hydroxylase inhibitor (P4-HI; IC50 value 3.9 μM for PHD2) that increases plasma EPO levels up to 30-fold in hemodialysis (HD) patients, and reduces cardiac remodeling after myocardial infarction in rats independent of a reduction of collagen maturation or altering growth factors. KEYWORDS: FG-2216 | supplier | PHD inhibitor | YM 311 | FG2216 | YM311 | CAS [223387-75-5] | Hypoxia-signaling cascade | PHD-2 (HIF1) | PHD-4 (HIF1) | Inhibitor | hypoxia inducible factor | prolyl hydroxylase | EPO | hemodialysis | cardiac remodeling | myocardial infarction | collagen
Orally active HIF-PHD inhibitor that increases plasma EPO levels in vivo
Chemical name2-(1-chloro-4-hydroxyisoquinoline-3-carboxamido)acetic acid Parent CAS No.[223387-75-5] |
| 產(chǎn)品資料 |
